Results 71 to 80 of about 23,717 (182)

TNF-alpha-induced cPLA2 expression via NADPH oxidase/reactive oxygen species-dependent NF-kappaB cascade on human pulmonary alveolar epithelial cells

Frontiers in Pharmacology, 2016
Tumor necrosis factor-alpha (TNF-alpha) triggers activation of cytosolic phospholipase A2 (cPLA2) and then enhancing the synthesis of prostaglandin (PG) in inflammatory diseases. However, the detailed mechanisms of TNF-alpha induced cPLA2 expression were
Chih-Chung Lin, Wei Ning Lin, Rou-Ling Cho, Chen-yu Wang, Li-Der Hsiao, Chuen-Mao Yang, Chuen-Mao Yang, Chuen-Mao Yang   +7 more
doaj   +1 more source

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

PLoS ONE, 2009
BackgroundIn response to viral infection, the innate immune system recognizes viral nucleic acids and then induces production of proinflammatory cytokines and type I interferons (IFNs).
Hiroyasu Konno, Takuya Yamamoto, Kohsuke Yamazaki, Jin Gohda, Taishin Akiyama, Kentaro Semba, Hideo Goto, Atsushi Kato, Toshiaki Yujiri, Takahiko Imai, Yasushi Kawaguchi, Bing Su, Osamu Takeuchi, Shizuo Akira, Yasuko Tsunetsugu-Yokota, Jun-ichiro Inoue   +15 more
doaj   +1 more source

Expression of CYLD, NF-kappaB and NF-kappaB-related factors in salivary gland tumors.

In vivo (Athens, Greece), 2006
The cylindromatosis (CYLD) gene was originally identified as a tumor suppressor that is mutated in familial cylindromatosis, an autosomal dominant condition that confers a predisposition to multiple tumors of the skin appendages. CYLD has deubiquitinating enzyme activity and inhibits the activation of transcription factor NF-kappaB.
Masakatsu, Fukuda, Fumie, Fukuda, Yuko, Horiuchi, Yuka, Oku, Seiji, Suzuki, Kaoru, Kusama, Hideaki, Sakashita   +6 more
openaire   +1 more source

At the crossroads of SUMO and NF-kappaB.

Molecular cancer, 2004
Recognition of pathogens by immune receptors leads to activation of macrophages, dendritic cells, and lymphocytes. Signals are communicated to enhance expression of target molecules such as cytokines and adhesion molecules, depending on activation of various inducible transcription factors, among which the family NF-kappaB transcription factors plays ...
Martin P, Kracklauer, Christian, Schmidt
openaire   +1 more source

TNFAIP3 interacting protein 2 relieves lipopolysaccharide (LPS)-induced inflammatory injury in endometritis by inhibiting NF-kappaB activation. [PDF]

Immun Inflamm Dis, 2023
Qian X, Wang Y, Li X, Li Y, Li L.
europepmc   +1 more source

Intravenous Injection of PEI-Decorated Iron Oxide Nanoparticles Impacts NF-kappaB Protein Expression in Immunologically Stressed Mice. [PDF]

Nanomaterials (Basel), 2023
Schwarz C, Göring J, Grüttner C, Hilger I.   +3 more
europepmc   +1 more source

An Update on the Multifaceted Role of NF-kappaB in Endometriosis. [PDF]

Int J Biol Sci, 2022
Liu Y, Wang J, Zhang X.
europepmc   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway. [PDF]

Cancer Cell Int, 2022
Zhang X, Wang F, Yan F, Huang D, Wang H, Gao B, Gao Y, Hou Z, Lou J, Li W, Yan J.   +10 more
europepmc   +1 more source

Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes. [PDF]

Mediators Inflamm, 2022
Zhang X, Wang S, Wang W, Song L, Feng S, Wang J, Kang T, Yang P, Wang N, Yang P, Bai R, Shao Y, Zheng Y.   +12 more
europepmc   +1 more source