Results 81 to 90 of about 188,422 (163)

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Morphine exacerbates HIV-1 Tat-induced cytokine production in astrocytes through convergent effects on [Ca(2+)](i), NF-kappaB trafficking and transcription.

PLoS ONE, 2008
Astroglia are key cellular sites where opiate drug signals converge with the proinflammatory effects of HIV-1 Tat signals to exacerbate HIV encephalitis.
Nazira El-Hage, Annadora J Bruce-Keller, Tatiana Yakovleva, Igor Bazov, Georgy Bakalkin, Pamela E Knapp, Kurt F Hauser   +6 more
doaj   +1 more source

TNF Superfamily: A Growing Saga of Kidney Injury Modulators

Mediators of Inflammation, 2010
Members of the TNF superfamily participate in kidney disease. Tumor necrosis factor (TNF) and Fas ligand regulate renal cell survival and inflammation, and therapeutic targeting improves the outcome of experimental renal injury.
Maria D. Sanchez-Niño, Alberto Benito-Martin, Sara Gonçalves, Ana B. Sanz, Alvaro C. Ucero, Maria C. Izquierdo, Adrian M. Ramos, Sergio Berzal, Rafael Selgas, Marta Ruiz-Ortega, Jesus Egido, Alberto Ortiz   +11 more
doaj   +1 more source

Hsc70 is a novel interactor of NF-kappaB p65 in living hippocampal neurons [PDF]

, 2013
Klenke C, Widera D, Engelen T, et al. Hsc70 is a novel interactor of NF-kappaB p65 in living hippocampal neurons. PLoS ONE. 2013;8(6): e65280.Signaling via NF-κB in neurons depends on complex formation with interactors such as dynein/dynactin motor ...
Klenke, Christin, Kaltschmidt Christian, Christian Kaltschmidt, Thomas Noll, Christin Klenke, Karsten Niehaus, Kaltschmidt, Christian, Noll, Thomas, Kaltschmidt, Barbara, M. Lienhard Schmitz, Janine Müller, Klenke Christin, Müller, Janine, Darius Widera, Kaltschmidt Barbara, Widera, Darius, Engelen Thomas, Niehaus Karsten, Schmitz, M., Schmitz, M Lienhard, Widera, Darius ; https://orcid.org/, Niehaus, Karsten, Widera Darius, Noll, Thomas ; https://orcid.org/, Thomas Engelen, Müller Janine, Barbara Kaltschmidt, Noll Thomas, Schmitz M. Lienhard, Engelen, Thomas, M Lienhard Schmitz   +30 more
core   +1 more source

The peroxisome proliferator-activated receptor γ coactivator 1α/β (PGC-1) coactivators repress the transcriptional activity of NF-κB in skeletal muscle cells [PDF]

, 2013
A persistent, low-grade inflammation accompanies many chronic diseases that are promoted by physical inactivity and improved by exercise. The beneficial effects of exercise are mediated in large part by peroxisome proliferator-activated receptor γ ...
Handschin, Christoph, Eisele, Petra S, Eisele, Petra S., Salatino, Silvia, Hottiger, Michael O., Hottiger, Michael O, Sobek, Jens   +6 more
core   +1 more source

A Unique WHSC1L1‐FGFR1 Fusion in Follicular Dendritic Cell Sarcoma

Pathology International, Volume 76, Issue 8, August 2026.
Pedro Farrajota Neves da Silva, Felix Haglund de Flon, Clas Mercke, George Z. Rassidakis   +3 more
wiley   +1 more source

Comment on ‘Oxidative Stress‐Induced Expression Levels of PXDN and NF‐κB in Type 2 Diabetic Patients With Nephropathy’

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Rofia Ali, Muhammad Faizan Khan
wiley   +1 more source

IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway. [PDF]

, 2011
Interleukin-1β (IL-1β) is a pro-inflammatory cytokine that plays a key role in the pathogenesis of osteoarthritis (OA). Growth factors (GFs) capable of antagonizing the catabolic actions of cytokines may have therapeutic potential in the treatment of OA.
Franziska Busch, Azadeh Montaseri, Jafar Soleimani Rad, Busch, Franziska, Montaseri, Azadeh, Rad, Jafar Soleimani, Mehdi Shakibaei, Ali Mobasheri, Constance Aldinger, Aldinger, Constance, Shakibaei, Mehdi, Mobasheri, Ali, Constanze Buhrmann, Buhrmann, Constanze   +13 more
core   +2 more sources

The Neutrophil Gelatinase-associated lipocalin (NGAL), a NF-kB regulated gene, is a survival factor for thyroid neoplastic cells [PDF]

, 2008
NF-κB is constitutively activated in primary human thyroid tumors, particularly in those of anaplastic type. The inhibition of NF-κB activity in the human anaplastic thyroid carcinoma cell line, FRO, leads to an increased susceptibility to ...
Iannetti, Alessio
core   +1 more source

The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.

PLoS Pathogens, 2010
Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. Here we found that the type III effectors, NleE from enteropathogenic E.
Hayley J Newton, Jaclyn S Pearson, Luminita Badea, Michelle Kelly, Mark Lucas, Gavan Holloway, Kylie M Wagstaff, Michelle A Dunstone, Joan Sloan, James C Whisstock, James B Kaper, Roy M Robins-Browne, David A Jans, Gad Frankel, Alan D Phillips, Barbara S Coulson, Elizabeth L Hartland   +16 more
doaj   +1 more source