Results 221 to 230 of about 41,205 (276)

FOXC2 represses NFAT1-dependent transcription through a DNA-facilitated protein-protein interaction. [PDF]

open access: yesNucleic Acids Res
Chen X   +13 more
europepmc   +1 more source

Transcription factors of the NFAT family: regulation and function.

open access: yesAnnual Review of Immunology, 1997
▪ Abstract  As targets for the immunosuppressive drugs cyclosporin A and FK506, transcription factors of the NFAT (nuclear factor of activated T cells) family have been the focus of much attention.
A. Rao, C. Luo, P. Hogan
semanticscholar   +2 more sources

Calcineurin/NFAT signalling inhibits myeloid haematopoiesis

open access: yesEMBO Molecular Medicine, 2012
Nuclear factor of activated T cells (NFAT) comprises a family of transcription factors that regulate T cell development, activation and differentiation. NFAT signalling can also mediate granulocyte and dendritic cell (DC) activation, but it is unknown
Jan Frič   +2 more
exaly   +2 more sources

Alternative splicing and expression of human and mouse NFAT genes [PDF]

open access: yesGenomics, 2008
Four members of the nuclear factor of activated T cells (NFAT) family (NFATC1, NFATC2, NFATC3, and NFATC4) are Ca2+-regulated transcription factors that regulate several processes in vertebrates, including the development and function of the immune ...
Priit Pruunsild   +2 more
exaly   +2 more sources
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NFAT signaling in vertebrate development

Current Opinion in Genetics and Development, 2001
NFATc proteins transduce Ca(2+) signals to the nucleus and then pair with other proteins on DNA to generate NFAT complexes that activate transcription in response to both electrical and tyrosine kinase signaling. The four NFATc genes arose at the origin of vertebrates, implying that they have evolved for the development of vertebrate-specific functions,
Gerald Crabtree   +2 more
exaly   +3 more sources

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