Results 201 to 210 of about 15,571 (214)
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Noncanonical NFATc1 activation in DN thymocytes
Nature Immunology, 2013Double-negative (DN) thymocytes depend on interleukin 7 (IL-7) for survival. In DN2 and DN3 cells, a new role has now been identified for signaling via the IL-7 receptor and the kinase Jak3 that leads to noncanonical activation of the transcription factor NFATc1 and upregulation of expression of the antiapoptotic protein Bcl-2.
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Retinoic acid inhibits NFATc1 expression and osteoclast differentiation
Journal of Bone and Mineral Metabolism, 2011Ingestion of excess vitamin A appears to correlate with an increased fracture risk, an outcome that is likely mediated by retinoic acids (RAs); these are vitamin A metabolites that have dramatic effects on skeletal development. We studied the impacts of RA and isoform-specific RA receptor (RAR) agonists (α, β, and γ) on osteoclast formation ...
Wayne, Balkan +4 more
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NFATC1 modulation of atrial excitability in zebrafish
Biophysical Journal, 2023Natalia S. Torres +3 more
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Identification and characterization of NFATc1+ skeletal stem cells in bone regeneration
Cell Reports, 2022Ling Ye, Feifei Li
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Nfatc1 Promotes Interstitial Cell Formation During Cardiac Valve Development in Zebrafish
Circulation Research, 2020Didier Stainier +2 more
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