Results 21 to 30 of about 37,410 (228)

Human Lung Mast Cells Impair Corticosteroid Responsiveness in Human Airway Smooth Muscle Cells

Frontiers in Allergy, 2021
The mechanisms underlying corticosteroid insensitivity in severe asthma have not been elucidated although some indirect clinical evidence points toward a role of mast cells.
Abdulrahman Alzahrani, Abdulrahman Alzahrani, Jameel Hakeem, Michael Biddle, Fahad Alhadian, Aamir Hussain, Latifa Khalfaoui, Katy M. Roach, Omar Tliba, Peter Bradding, Yassine Amrani   +10 more
doaj   +1 more source

Molecular characterisation of Neisseria gonorrhoeae associated with disseminated gonococcal infections in Queensland, Australia: a retrospective surveillance study

BMJ Open, 2022
Objectives Gonorrhoea caused by Neisseria gonorrhoeae is the second most notified sexually transmitted infection (STI) in Australia and the case numbers for this STI have been increasing globally. Progressive gonococcal infection may lead to disseminated
David M Whiley, Colleen L Lau, Christine J D Guglielmino, Sumeet Sandhu, Cameron Buckely, Ella Trembizki, Amy V Jennison   +6 more
doaj   +1 more source

Surveillance and molecular epidemiology of Neisseria gonorrhoeae isolates in Shenzhen, China, 2010–2017

Journal of Global Antimicrobial Resistance, 2020
Objectives: The development and emergence of antimicrobial resistance in Neisseria gonorrhoeae (NG) have become a major public-health problem worldwide.
Feng Wang, Jing-Wei Liu, Yi-Zhun Li, Li-Jun Zhang, Jing Huang, Xiang-Sheng Chen, Shao-Chun Chen, Yue-Ping Yin   +7 more
doaj   +1 more source

Molecular characterization of Neisseria gonorrhoeae isolates in Almaty, Kazakhstan, by VNTR analysis, Opa-typing and NG-MAST

Infection, Genetics and Evolution, 2012
In the present study, new variable number tandem repeats (VNTR) loci in the Neisseria gonorrhoeae genome were identified in silico. VNTR analysis scheme using PCR and agarose or polyacrylamide gel electrophoresis was developed based on nine VNTR loci with various degrees of polymorphism.
Anastasiya V, Kushnir, Talgat A, Muminov, Assylzhan I, Bayev, Evgeny A, Khrapov, Maxim L, Filipenko   +4 more
openaire   +2 more sources

The use of current genotyping assay methods for Neisseria gonorrhoeae

Vestnik Dermatologii i Venerologii, 2017
The review deals with up-to-date genotyping assay methods of Neisseria gonorrhoeae. The review covers the characteristics and features of each method, application areas of genotyping assay of Neisseria gonorrhoeae. The methods described enable to upgrade
M. V. Shpilevaya, O. A. Obraztsova, A. V. Chestkov   +2 more
doaj   +1 more source

P3.282 Multi-Antigen Sequence Types (NG-MAST) and Antimicrobial Susceptibilities onNeisseria GonorrhoeaeIsolated in Canada, 2010–2011 [PDF]

Sexually Transmitted Infections, 2013
Background Neisseria gonorrhoeae have acquired resistance to many antibiotics and have developed decreasing susceptibilities to 3rd generation cephalosporins. Method NG-MAST sequence types and minimum inhibitory concentration (MICs) by agar dilution were determined for each N.
I Martin, P Sawatzky, G Liu, V Allen, L Hoang, B Lefebvre, M Lovgren, T Wong   +7 more
openaire   +1 more source

P05.07 Neisseria gonorrhoeaemultiantigen sequence typing (ng-mast) of isolates collected from std patients in delhi, india [PDF]

Sexually Transmitted Infections, 2015
Background Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) is a highly discriminatory technique for assessing the genetic diversity of N. gonorrhoeae and has also been put forward as a tool for predicting specific antimicrobial resistance (AMR) phenotypes.
S Sood, N Mahajan, R Singh, A Kapil, BK Das, V Sreenivas, HK Kar, VK Sharma   +7 more
openaire   +1 more source

Tryptase in children in the practice of an allergist

Аллергология и Иммунология в Педиатрии, 2023
The normal serum tryptase level is 0–11.4 ng/ml. Hypertryptasemia occurs with anaphylaxis, systemic mastocytosis, and cutaneous mastocytosis in children. Recently, mast cell activation syndromes are increasingly being diagnosed. The article discusses the
D. Sh. Macharadze
doaj   +1 more source

Unique combined penA/mtrR/porB mutations and NG-MAST strain types associated with ceftriaxone and cefixime MIC increases in a ‘susceptible’ Neisseria gonorrhoeae population [PDF]

Journal of Antimicrobial Chemotherapy, 2014
To determine which mutations in penA, mtrR and porB are implicated in increasing minimum MICs of ceftriaxone and cefixime in a susceptible gonococcal population and to ascertain associations with gonococcal strain types (STs).One hundred and forty-six Neisseria gonorrhoeae isolates formed two extended-spectrum cephalosporin susceptibility groups: group
S D, Thakur, S, Starnino, G B, Horsman, P N, Levett, J R, Dillon   +4 more
openaire   +2 more sources

Antimicrobial resistance (AMR) and molecular characterization of Neisseria gonorrhoeae in Ghana, 2012-2015.

PLoS ONE, 2019
Neisseria gonorrhoeae antimicrobial resistance (AMR) surveillance is essential for tracking the emergence and spread of AMR strains in local, national and international populations. This is crucial for developing or refining treatment guidelines.
Naiki Attram, Bright Agbodzi, Helena Dela, Eric Behene, Edward O Nyarko, Nicholas N A Kyei, John A Larbi, Bernard W L Lawson, Kennedy K Addo, Mercy J Newman, Christopher A Duplessis, Nehkonti Adams, Magnus Unemo, Andrew G Letizia   +13 more
doaj   +1 more source