Results 41 to 50 of about 380,610 (181)
AI-accelerated therapeutic antibody development: practical insights
Frontiers in Drug DiscoveryAntibodies represent the largest class of biotherapeutics thanks to their high target specificity, binding affinity and versatility. Recent breakthroughs in Artificial Intelligence (AI) have enabled information-rich in silico representations of ...
Luca Santuari +4 more
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Sky coverage modeling for the whole sky for laser guide star multiconjugate adaptive optics [PDF]
, 2012 The scientific productivity of laser guide star adaptive optics systems strongly depends on the sky coverage, which describes the probability of finding natural guide stars for the tip/tilt wavefront sensor(s) to achieve a certain performance.
Andersen, David +2 more
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Evaluation of GenDx Protocol for HLA NGS Genotyping Using the Ion Torrent Sequencing Platform
Acta Medica Bulgarica, 2023 The Human Major Histocompatibility Complex (HLA) is the most polymorphic region of the human genome and encodes molecules with a central role in antigen-specific immune responses.
Ormandjieva A., Ivanova M.
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Systematic detection of mosaicism by using digital NGS reveals three new MEN1 mosaicisms
Endocrine Connections, 2022 Purpose: Mosaicism is a feature of several inherited tumor syndromes. Only a few cases of mosaicism have been described in multiple endocrine neoplasia type 1 (MEN1).
Arnaud Lagarde +13 more
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A note on the shortest common superstring of NGS reads
, 2016 The Shortest Superstring Problem (SSP) consists, for a set of strings S = {s_1,...,s_n}, to find a minimum length string that contains all s_i, 1
Braquelaire, Tristan +3 more
core +2 more sources
Atmospheric tomography with separate minimum variance laser and natural guide star mode control [PDF]
, 2009 This paper introduces a novel, computationally efficient, and practical atmospheric tomography wavefront control architecture with separate minimum variance laser and natural guide star mode estimation.
Ellerbroek, B. L., Gilles, L.
core +1 more source
Frontiers in MicrobiologyIntroductionThe appendix is thought to act as a regulatory immune organ and gut microbiota reservoir. Although appendectomy is linked to health risks, its impact on the gut microbiota remains understudied.MethodsThis study is conceived as a cross ...
Matija Hadžić +6 more
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Diagnostic applications of next generation sequencing: working towards quality standards [PDF]
, 2012 Over the past 6 years, next generation sequencing (NGS) has been established as a valuable high-throughput method for research in molecular genetics and has successfully been employed in the identification of rare and common genetic variations. All major
Adey +42 more
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Central European Journal of Immunology, 2021 Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid neoplasms characterized by the presence of cytopenias, ineffective hematopoiesis and frequent transformation into secondary acute myeloid leukemia (secAML).
Monika Małgorzata Adamska +11 more
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A new targeted CFTR mutation panel based on next-generation sequencing technology [PDF]
, 2017 Searching for mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR) is a key step in the diagnosis of and neonatal and carrier screening for cystic fibrosis (CF), and it has implications for prognosis and personalized therapy ...
Alberti, Luisella +10 more
core +2 more sources