Results 71 to 80 of about 87,888 (339)

Niacin Attenuates Pulmonary Hypertension Through H-PGDS in Macrophages

Circulation Research, 2020
Supplemental Digital Content is available in the text. Rationale: Pulmonary arterial hypertension (PAH) is characterized by progressive pulmonary vascular remodeling, accompanied by varying degrees of perivascular inflammation.
Daile Jia, Peiyuan Bai, Naifu Wan, Jiao Liu, Qian Zhu, Yuhu He, Guilin Chen, Jing Wang, Han Chen, Chen Wang, Ankang Lyu, M. Lazarus, Yunchao Su, Y. Urade, Ying Yu, Jian Zhang, Yujun Shen   +16 more
semanticscholar   +1 more source

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

Advanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang, Xiao‐Mei Zhang, Xi Wu, Cheng‐Kai Zhou, Zhen‐Zhen Liu, Xue‐Yue Luo, Liang Zhang, Wei Chen, Yong‐Jun Yang   +8 more
wiley   +1 more source

Association between dietary intake of niacin and stroke in the US residents: evidence from national health and nutrition examination survey (NHANES) 1999–2018

Frontiers in Nutrition
ObjectiveThis study aims to explore the association between niacin intake and stroke within a diverse, multi-ethnic population.MethodsA stringent set of inclusion and exclusion criteria led to the enrollment of 39,721 participants from the National ...
Jie-Yu Qiu, Wen-Hui Zhang, Xiao-Ming Zhu, Li-Da Wu, Ji-Hua Huang, Jie Zhang   +5 more
doaj   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Evaluation of Physicochemical Properties of Defatted Rice Bran Protein Concentrate Obtained by Modified IP–EWT Process

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives The IP–EWT is a protein recovery and purification process that combined with isoelectric precipitation (IP) and electrolyzed water treatment (EWT) to produce highly nutritious, hypoallergenic protein from heat‐stabilized defatted rice bran (HSDFRB).
Keiko Ueda, Charin Techapun, Noppol Leksawasdi, Thanongsak Chaiyaso, Naomi Abe‐Kanoh, Masanori Watanabe   +5 more
wiley   +1 more source

The facts behind niacin [PDF]

Therapeutic Advances in Cardiovascular Disease, 2011
Although low-density lipoprotein cholesterol (LDL-C) lowering represents the mainstay of current lipid treatment, high-density lipoprotein cholesterol (HDL-C) has generated increasing interest as a secondary therapeutic target because of strong evidence that serum HDL-C concentration is inversely associated with coronary heart disease risk.
David D. Berg, Willibald Hochholzer, Robert P. Giugliano   +2 more
openaire   +3 more sources

Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway

International Journal of Molecular Sciences, 2020
Mastitis is one of three bovine diseases recognized as a cause of substantial economic losses every year throughout the world. Niacin is an important feed additive that is used extensively for dairy cow nutrition.
Wenjin Guo, Juxiong Liu, Wen Li, He Ma, Qian Gong, Xingchi Kan, Yu Cao, Jianfa Wang, Shoupeng Fu   +8 more
semanticscholar   +1 more source

Vitamins Are Retained in Fortified Whole‐Grain Maize Meal When Stored Under Tropical Conditions When Optimal Storage Practices Are Used

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objective To ensure provision of essential micronutrients to at‐risk maize‐consuming populations, their stability in stored fortified whole‐grain maize meal (FWGMM) is essential. Vitamin stability in commercial FWGMM was studied over 6 months under two real‐world tropical conditions (overall average 25.3°C, 53.5% relative ...
John R. N. Taylor, Tilana Graaff, Johnes David, David Kamau, Darshana Joshi, Benjamin Byinshi, Corinda Erasmus, Peiman Milani, Henriëtte L. de Kock   +8 more
wiley   +1 more source

Should liver enzymes be checked in a patient taking niacin? [PDF]

, 2005
No randomized trials directly address the question of frequency of liver enzyme monitoring with niacin use. Niacin use is associated with early and late hepatotoxicity (strength of recommendation [SOR]: B, based on incidence data from randomized ...
Brown, Marcy L., Mertens, Marsha K., Rizkallah, Gloria S.   +2 more
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