Results 81 to 90 of about 33,803 (193)

A Case Report of Familial Chylomicronemia Syndrome With Infantile Onset: One‐Year Follow‐Up on Lipid Profile and Growth Development

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive disease caused by a biallelic loss‐of‐function mutation in the lipoprotein lipase (LPL) gene or its cofactors. This case report describes the diagnosis, management, and one‐year follow‐up of an infant with FCS.
Jinyi Liu, Xuanyu Meng, Yi Wu, Guosheng Huang, Shuheng Liang   +4 more
wiley   +1 more source

Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol.

PLoS ONE, 2013
ObjectiveNiacin potently lowers triglycerides, mildly decreases LDL-cholesterol, and largely increases HDL-cholesterol. Despite evidence for an atheroprotective effect of niacin from previous small clinical studies, the large outcome trials, AIM-HIGH and
Susan Kühnast, Mieke C Louwe, Mattijs M Heemskerk, Elsbet J Pieterman, Jan B van Klinken, Sjoerd A A van den Berg, Johannes W A Smit, Louis M Havekes, Patrick C N Rensen, José W A van der Hoorn, Hans M G Princen, J Wouter Jukema   +11 more
doaj   +1 more source

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

eFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang, Ling Wei, Kaibing Zhou, Qin Deng, Muhammad Mobeen Tahir, Hongxia Wu, Minjie Qian   +6 more
wiley   +1 more source

Cystoid Macular Edema Induced by Low Doses of Nicotinic Acid

Case Reports in Ophthalmological Medicine, 2013
Cystoid macular edema (CME) is a condition that involves the macula, causing painless vision loss. In this paper, we report a case of niacin-induced bilateral cystoid macular edema (CME) in a middle-age woman taking low dose of niacin (18 mg of ...
Daniela Domanico, Carmela Carnevale, Serena Fragiotta, Francesca Verboschi, Simona Altimari, Enzo Maria Vingolo   +5 more
doaj   +1 more source

Dose Titration of Plant‐Based Flavonoid Blend Supplementation on Performance, Digestibility, Gut Microbiome, Blood Biomarkers, and Meat Quality of Growing Rabbits

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Plant‐based flavonoid blend (PFB) at 0.60 g/kg diet produced the best growth performance, feed efficiency, and dry matter digestibility in growing rabbits. It also improved gut microbiome balance and increased serum high‐density lipoprotein‐cholesterol.
Md. Aliar Rahman, Md. Mehedi Hasan, Md. Abul Hashem, Mahbubul Pratik Siddique, Rakhi Chowdhury   +4 more
wiley   +1 more source

Reconceptualizing Dyslipidemia: Diversity of Lipid Imbalances and Their Clinical Implications; A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims The traditional definition of dyslipidemia focuses on isolated lipid changes (LDL‐C, HDL‐C, triglycerides) and may not fully capture the biological complexity or clinical variability of lipid imbalances. Recent evidence challenges this narrow view, suggesting that dyslipidemia involves broader disruptions in lipid ...
Ali Mansoursamaei, Amirhossein Yadegar, Fatemeh Mohammadi, Seyed Arsalan Seyedi, Soghra Rabizadeh, Sahar Karimpour Reyhan, Alireza Esteghamati, Manouchehr Nakhjavani   +7 more
wiley   +1 more source

Association of dietary niacin intake with the prevalence and incidence of chronic obstructive pulmonary disease

Scientific Reports
Evidence regarding the association between dietary niacin intake and chronic obstructive pulmonary disease (COPD) is limited. Our study investigates the relationship between dietary niacin intake and the prevalance and incidence of COPD in the adult ...
Wen-Wen Li, Kun-Lun Ren, Jia Yu, Hai-Sheng Guo, Ben-Hong Liu, Yang Sun   +5 more
doaj   +1 more source

Association between niacin intake and chronic kidney disease in male participants—a cross-sectional study from the NHANES (2005–2018)

Frontiers in Nutrition
BackgroundChronic kidney disease (CKD), a significant health challenge in the United States, often progresses from asymptomatic conditions to advanced stages and exhibits a higher prevalence among male individuals.
Cong Hu, Ting Tang
doaj   +1 more source

Structural basis for a p21‐activated kinase 4 and nicotinamide phosphoribosyltransferase dual inhibitor

Acta Crystallographica Section D, Volume 82, Issue 8, Page 972-981, August 2026.
The 2‐aminopyridine moiety of KPT‐7523 binds p21‐activated kinase 4 and nicotinamide phosphoribosyltransferase, enabling a versatile design for multi‐target cancer therapy.Simultaneous inhibition of oncogenic signaling and metabolic pathways represents a promising approach for cancer therapy.
Jaehui Park, Hye Rim Hong, Sang Hyun Han, Jinsue Song, Se-Young Son, Saehae Choi, Sang Mi Park, Won-Kyu Lee, Chimari Jiko, Ji-Hun Kim, Jun-Goo Jee, Jeong Kyu Bang, Il Yeong Park, Soo Jae Lee   +13 more
wiley   +1 more source

Effect of dietary niacin on immune response, apoptosis and microbial community in the intestine of juvenile turbot (Scophthalmus maximus L.)

Aquaculture Reports
A ten-week feeding trial was conducted to investigate the effect of dietary niacin on intestinal health of juvenile turbot. Three isonitrogenous and isolipidic experimental diets were formulated, containing 0 (NA0, as control), 20 (NA20), and 80 (NA80 ...
Xiaoyuan Ge, Jintao Pan, Prakaiwan Yongyut, Orapint Jintasataporn, Junming Deng, Kangsen Mai, Yanjiao Zhang   +6 more
doaj   +1 more source