Results 71 to 80 of about 33,672 (206)

Niacin-induced lysosomal free cholesterol efflux via LXRα-mediated signaling pathways in macrophages retards the progression of atherosclerosis

Heliyon
Background: Lysosomal free cholesterol efflux plays a crucial role in foam cell formation and atherogenesis. In addition to its lipid-modifying functions, whether the direct effect of niacin on lysosomal cholesterol efflux contributes to its anti ...
Hao Xu, Xueni Sun, Miaoru Peng, Yuanshu Zhao, Shuxian Li, Ping Li, Fan Zhang, Xiaodong Fu, Xiaoyang Xu   +8 more
doaj   +1 more source

Effects of Dietary Activated Charcoal Supplementation on Performance, Egg Quality, and Bone Calcification in Laying Hens Exposed to High Fluoride

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT The aim of the present study was to determine the effects of high dietary fluoride intake on performance, egg quality, serum biochemical parameters, bone tissue, mineral accumulation, and the expression of selected mineralisation‐related genes in laying hens, and to evaluate whether these effects could be alleviated by dietary activated ...
Muhammed Serkan Sevim, Emre Yilmaz
wiley   +1 more source

Association between dietary niacin intake and mortality among US individuals with chronic obstructive pulmonary disease: data from the national health and nutrition examination survey 1999–2018

Frontiers in Nutrition
Background and aimsChronic obstructive pulmonary disease (COPD) is a long-lasting condition that significantly hinders respiratory function. Niacin, a crucial nutrient in the diet, is essential for maintaining general health.
Chengfeng Fu, Chengfeng Fu, Lixia Zhang, Jing Luo, Yingying Zhang   +4 more
doaj   +1 more source

Evaluation of Torula Yeast (Candida utilis) Single Cell Proteins as a Partial Replacement for Soybean Meal in Broiler Diets: Effects on Productive Performance, Meat Quality Traits, and Plasma Metabolome

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Over recent years the use of yeast in feedstuffs has gained momentum due to novel developments in single‐cell proteins (SCPs). SCPs are considered a sustainable protein source, as their production enable to convert low‐value substrates (including industrial/agricultural wastes) into feed, with a related reduced environmental impact. This study
Jonathan Dayan, Marco Zampiga, Francesca Soglia, Luca Laghi, Elisa Benini, Massimiliano Petracci, Federico Sirri   +6 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Pinus‐derived membrane vesicles disrupt pathogenic metabolism in fungi

Plant Biology, EarlyView.
Needle‐derived vesicles from pine trees impair fungal metabolism and growth, offering a sustainable strategy to control pine pitch canker disease. Abstract Much of what we know about the biological impacts of vesicles (MVs) is derived from Arabidopsis thaliana.
S. Kunene, T. J. Mmushi, E. Steenkamp, T. Motaung   +3 more
wiley   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

The Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga, Matheus B. Rocha, Ana P. Morelli, Raul G. da Costa, Marcelo A. S. Mori, Adelino S. R. da Silva, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle   +8 more
wiley   +1 more source

A nonlinear threshold association between daily food niacin intake and erectile dysfunction among adult male in the United States: a cross-sectional study

Critical Public Health
The role of nutrition in erectile dysfunction (ED) is gaining attention, yet the specific association with dietary niacin—a key nutrient for vascular function—remains unclear, highlighting a significant evidence gap.
Wenzhong Zheng, Jianwei Wu, Longlong Fan, Shiqiang Zhang   +3 more
doaj   +1 more source

Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol.

PLoS ONE, 2013
ObjectiveNiacin potently lowers triglycerides, mildly decreases LDL-cholesterol, and largely increases HDL-cholesterol. Despite evidence for an atheroprotective effect of niacin from previous small clinical studies, the large outcome trials, AIM-HIGH and
Susan Kühnast, Mieke C Louwe, Mattijs M Heemskerk, Elsbet J Pieterman, Jan B van Klinken, Sjoerd A A van den Berg, Johannes W A Smit, Louis M Havekes, Patrick C N Rensen, José W A van der Hoorn, Hans M G Princen, J Wouter Jukema   +11 more
doaj   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source