Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation [PDF]
Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which leads to dermatitis, diarrhea, dementia, and possibly death depending on its severity and duration.
Yong Chool Boo
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Disruptive DNA Intercalation Is the Mode of Interaction Behind Niacinamide Antimicrobial Activity [PDF]
Niacinamide was recently shown to directly interact with bacterial DNA and interfere with cell replication; niacinamide mode of interaction and efficacy as a natural anti-microbial molecule were also described.
Michal Rasis, Noa Ziklo, Paul Salama
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This study aims to prepare different types of Cu(II)-niacinamide complexes by layered solution method from various source of Cu(II) salts (sulphate, nitrate, chloride, and acetate) and in various M(II):niacinamide molar ratio (1:2, 1:4, and 1:6).
Nadia Cikita Handayani +4 more
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Functional Requirement of Niacinamide for Blood Profiles, Antioxidant Status, and Intestinal Health in Finishing Pigs Fed a Low-Protein Diet [PDF]
This study investigated the effects of dietary niacinamide supplementation on blood parameters, antioxidant status, and intestinal health in finishing pigs fed low-protein diets. Sixty-four pigs (Duroc × Landrace × Yorkshire; 80.4 ± 0.1 kg) were randomly
Yan Zhao +11 more
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Effects of dietary glycerol, vitamin C and niacinamide supplementation on liver of growing-finishing pigs [PDF]
The influence of supplementing glycerol, vitamin C and niacinamide on the liver of growing-finishing pigs has not yet been examined. This study investigated the effect of 10% glycerol, 0.06% vitamin C and 0.05% niacinamide supplementation at single or ...
Wenchen Sun +14 more
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Clinical Safety and Efficacy of Hyaluronic Acid–Niacinamide–Tranexamic Acid Injectable Hydrogel for Multifactorial Facial Skin Quality Enhancement with Dark Skin Lightening [PDF]
Facial aging is a complex process manifesting as skin hyperpigmentation, textural irregularities, and a diminished elasticity, hydration, and evenness of tone.
Sarah Hsin +8 more
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Impacts of 360 mg/kg Niacinamide Supplementation in Low-Protein Diets on Energy and Nitrogen Metabolism and Intestinal Microbiota in Growing–Finishing Pigs [PDF]
This study aimed to investigate the effects of adding 360 mg/kg niacinamide (NAM) to diets on nutrient metabolism, providing insights into how dietary NAM supplementation enhances nitrogen utilization and growth performance in pigs.
Xiaoyi Long +7 more
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Dermal Delivery of Niacinamide—In Vivo Studies [PDF]
In vivo human studies are considered to be the “gold standard” when investigating (trans)dermal delivery of actives. Previously, we reported the effects of a range of vehicles on the delivery of niacinamide (NIA) using conventional Franz cell studies. In
Yanling Zhang +5 more
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Topical delivery of niacinamide: Influence of neat solvents [PDF]
Niacinamide (NIA) has been widely used in cosmetic and personal care formulations for several skin conditions. Permeation of topical NIA has been confirmed in a number of studies under infinite dose conditions. However, there is limited information in the literature regarding permeation of NIA following application of topical formulations in amounts ...
Fotis Iliopoulos +5 more
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Yun-Ho Choi, Jae Young Shin, Jaeyoon Kim, Nae-Gyu Kang, Sanghwa Lee LG Household & Health Care (LG H&H) R&D Center, Seoul, 07795, KoreaCorrespondence: Sanghwa LeeLG Household & Health Care (LG H&H) R&D Center, 70, Magokjoongang 10-ro, Gangseo-gu, Seoul ...
Choi YH, Shin JY, Kim J, Kang NG, Lee S
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