Results 1 to 10 of about 12,548 (263)

Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation [PDF]

Antioxidants, 2021
Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which leads to dermatitis, diarrhea, dementia, and possibly death depending on its severity and duration.
Yong Chool Boo
doaj   +3 more sources

Clinical Safety and Efficacy of Hyaluronic Acid–Niacinamide–Tranexamic Acid Injectable Hydrogel for Multifactorial Facial Skin Quality Enhancement with Dark Skin Lightening [PDF]

Gels
Facial aging is a complex process manifesting as skin hyperpigmentation, textural irregularities, and a diminished elasticity, hydration, and evenness of tone.
Sarah Hsin, Kelly Lourenço, Alexandre Porcello, Michèle Chemali, Cíntia Marques, Wassim Raffoul, Marco Cerrano, Lee Ann Applegate, Alexis E. Laurent   +8 more
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Efficacy and Skin Microbiome Modulation Effects of a Fixed-Concentration Combination of Benzoyl Peroxide 4% Plus Niacinamide 4% in a Film-Forming Cream in Subjects with Mild-to-Moderate Acne: A Non-Sponsored, Prospective, Assessor-Blinded, Pilot Trial [PDF]

Cosmetics
Benzoyl peroxide (BPO) and niacinamide (Niac) are commonly used alone or in combination with other molecules in the treatment of acne. BPO and Niac in the same product could exert complementary and synergistic effects improving efficacy in acne ...
Mario Puviani, Klaus Eisendle
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Disruptive DNA Intercalation Is the Mode of Interaction Behind Niacinamide Antimicrobial Activity [PDF]

Microorganisms
Niacinamide was recently shown to directly interact with bacterial DNA and interfere with cell replication; niacinamide mode of interaction and efficacy as a natural anti-microbial molecule were also described.
Michal Rasis, Noa Ziklo, Paul Salama
doaj   +3 more sources

Synthesis, characterization, and antibacterial activity of anion-depended Cu(II)-Niacinamide complexes

Kuwait Journal of Science, 2023
This study aims to prepare different types of Cu(II)-niacinamide complexes by layered solution method from various source of Cu(II) salts (sulphate, nitrate, chloride, and acetate) and in various M(II):niacinamide molar ratio (1:2, 1:4, and 1:6).
Nadia Cikita Handayani, Rio Risandiansyah, Anna Safitri, Yudi Purnomo, Yuniar Ponco Prananto   +4 more
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Mechanistic Insights into the Multiple Functions of Niacinamide: Therapeutic Implications and Cosmeceutical Applications in Functional Skincare Products [PDF]

Antioxidants
Niacinamide (or nicotinamide) is a small-molecule hydrosoluble vitamin with essential metabolic functions in mammalian cells. Niacinamide has become a key functional ingredient in diverse skincare products and cosmetics. This vitamin plays a pivotal role
Cíntia Marques, Farid Hadjab, Alexandre Porcello, Kelly Lourenço, Corinne Scaletta, Philippe Abdel-Sayed, Nathalie Hirt-Burri, Lee Ann Applegate, Alexis Laurent   +8 more
doaj   +3 more sources

Niacinamide Antimicrobial Efficacy and Its Mode of Action via Microbial Cell Cycle Arrest [PDF]

Microorganisms
Niacinamide is a versatile compound widely used in the personal care industry for its ample skin benefits. As a precursor to nicotinamide adenine dinucleotide (NAD+), essential for ATP production and a substrate for poly-ADP-ribose polymerase-1 (PARP-1),
Noa Ziklo, Maayan Bibi, Lior Sinai, Paul Salama   +3 more
doaj   +3 more sources

Functional Requirement of Niacinamide for Blood Profiles, Antioxidant Status, and Intestinal Health in Finishing Pigs Fed a Low-Protein Diet [PDF]

Animals
This study investigated the effects of dietary niacinamide supplementation on blood parameters, antioxidant status, and intestinal health in finishing pigs fed low-protein diets. Sixty-four pigs (Duroc × Landrace × Yorkshire; 80.4 ± 0.1 kg) were randomly
Yan Zhao, Fangli Tang, Yunlong Shi, Qinyu Tan, Qingxin Ju, Ziyi Yang, Guanqing Yang, Pengfei Gao, Sung Woo Kim, Lin Xi, Guoqing Cao, Bugao Li   +11 more
doaj   +3 more sources

Pilot Study on the Effects of a Cosmetic Serum Containing Niacinamide, Postbiotics and Peptides on Facial Skin in Healthy Participants: A Randomized Controlled Trial [PDF]

Life
The literature describes niacinamide, but also postbiotics and peptides, as ingredients that improve skin barrier function, but also affect melanin and sebum levels in individuals.
Doris Rusic, Magdalena Ivic, Ana Slugan, Dario Leskur, Darko Modun, Toni Durdov, Dubravka Vukovic, Josipa Bukic, Josko Bozic, Ana Seselja Perisin   +9 more
doaj   +3 more sources

Dietary Supplementation of Crossbred Pigs with Glycerol, Vitamin C, and Niacinamide Alters the Composition of Gut Flora and Gut Flora-Derived Metabolites [PDF]

Animals
The addition of glycerin, vitamin C, and niacinamide to pig diets increased the redness of longissimus dorsi; however, it remains unclear how these supplements affect gut microbiota and metabolites.
Panting Wei, Wenchen Sun, Shaobin Hao, Linglan Deng, Wanjie Zou, Huadong Wu, Wei Lu, Yuyong He   +7 more
doaj   +3 more sources