Results 71 to 80 of about 13,295 (270)

Reduction of blood serum cholesterol [PDF]

open access: yes, 1974
By feeding a human subject as the sole source of sustenance a defined diet wherein the carbohydrate consists substantially entirely of glucose, maltose or a polysaccharide of glucose, the blood serum cholesterol level of the human subject is ...
Winitz, M.
core   +1 more source

Advanced Topical Formulations (ATF) [PDF]

open access: yes, 2016
Topical formulations aim to target the skin for a variety of cosmetic, protective or therapeutic needs. Despite the use of creams and ointments over the millennia, the bioavailability of actives from topical preparations remains quite low, often not ...
Hadgraft, J, Lane, M
core   +1 more source

The exposomal imprint on rosacea: More than skin deep

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki   +3 more
wiley   +1 more source

Synthesis and Pesticidal Activity of New Niacinamide Derivatives Containing a Flexible, Chiral Chain

open access: yesMolecules, 2022
Natural products are a source for pesticide or drug discovery. In order to discover lead compounds with high fungicidal or herbicidal activity, new niacinamide derivatives derived from the natural product niacinamide, containing chiral flexible chains ...
Zhe-Cheng Wei   +11 more
doaj   +1 more source

Global consensus on the management of melanin hyperpigmentation disorders

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron   +9 more
wiley   +1 more source

Toward understanding myometrial regulation : metabolomic investigation reveals new pathways of oxytocin and ritodrine activity on the myometrium [PDF]

open access: yes, 2016
In recent times, additional pathways involved in the regulation of the myometrium have been suggested. This also holds true for the effect of drugs such as oxytocin (OT) and β-adrenergic agonists on the myometrium.
Bafor, Enitome E.   +2 more
core   +1 more source

Prevention of Atopic Dermatitis in High‐Risk Infants: A Review of the Role of Lipid‐Based Barrier Repair Therapy

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan   +1 more
wiley   +1 more source

Paraneoplastic pemphigus with airway involvement

open access: yesRespiratory Medicine Case Reports
We report a case of paraneoplastic pemphigus presenting with acute hypoxemic respiratory failure due to bronchiolitis obliterans which improved with high dose systemic corticosteroids, rituximab, niacinamide and doxycycline.
Oscar A. Estrada Paz, Timothy J. Young
doaj   +1 more source

Bullous dermatoses secondary to anti-PD-L1 agents: a case report and review of the literature [PDF]

open access: yes, 2019
Immune checkpoint inhibitors are used to treat numerous malignancies but may be associated with severe adverse events. Bullous dermatoses, chiefly bullous pemphigoid (BP), are potentially progressive adverse events that cause blistering skin lesions and ...
Choi, Jennifer N   +3 more
core  

Nicotinamide treatment in a murine model of familial tumoral calcinosis reduces serum Fgf23 and raises heart calcium [PDF]

open access: yes, 2014
Mutations in the GALNT3 gene result in familial tumoral calcinosis, characterized by persistent hyperphosphatemia and ectopic calcific masses in soft tissues.
Gray, Amie K.   +3 more
core   +1 more source

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