Results 181 to 190 of about 256,874 (388)

On the mechanism of Dehydroquinate synthase : a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science in Chemistry [PDF]

open access: yes, 2001
The aim of this thesis is to investigate the influence of fluorine substitution on the second reaction of the shikimate pathway catalysed by the enzyme 3-dehydroquinate synthase.
Kathirgamanathan, Kalyani
core  

SP1‐Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Laser capture microdissection‐based proteomics of pancreatic intraepithelial neoplasia (PanIN) identifies specificity protein 1 (SP1) as a key driver of tumorigenesis and progression in pancreatic cancer through glycolytic remodeling. SP1 enhances aerobic glycolysis by transcriptionally activating 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase ...
Hexing Hang   +21 more
wiley   +1 more source

Leveraging Electrons for Electrochemical CO2 Capture Using a Hemi‐Labile Iron Complex

open access: yesAngewandte Chemie, EarlyView.
We present an electrochemical CO2 capture system using coordination complex with an iron center and hemi‐labile ligands. This system achieves an electron utilization of 1.43 by leveraging oxidation‐state‐dependent ligand coordination, enabling efficient CO2 separation from flue gas with low energy consumption and high cyclability.
Hyowon Seo   +4 more
wiley   +2 more sources

Urinary N-methylnicotinamide and β-aminoisobutyric acid predict catch-up growth in undernourished Brazilian children [PDF]

open access: yes, 2015
Guerrant, RL   +10 more
core   +1 more source

Novel Role of Gut‐Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure

open access: yesAdvanced Science, EarlyView.
Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Lixiao Zhou   +15 more
wiley   +1 more source

Biocatalytic Alkylation of Ambident Nucleophiles Enables Selective N‐Functionalization of Heterocycles and Late‐Stage Modifications

open access: yesAngewandte Chemie, EarlyView.
N‐alkylated heteroarenes are key structural motifs in bioactive compounds, but their regioselective synthesis via coupling of readily available azoles with haloalkanes remains very challenging. Here, we present a mild biocatalytic approach that proceeds on gram‐scale, is highly chemo‐ and regioselective, offering rapid access to valuable N‐alkylated ...
Felipe Ospina   +10 more
wiley   +2 more sources

Nicotinamide Counteracts Ultraviolet-B-Induced Cytotoxic Effects and Aquaporins Overexpression in the A375 Melanoma Cell Line

open access: yesDermato
Background/objectives: Ultraviolet-B (UVB) represents a major extrinsic factor in skin cancer development, causing cellular changes that are not yet fully understood. Aquaporins (AQPs) are a family of transmembrane proteins that favor water transport and
Lara Camillo   +4 more
doaj   +1 more source

Improving the Thermoelectric Properties of Conjugated Polymer Thin Films by Dip Coating – but not through Alignment

open access: yesAdvanced Electronic Materials, EarlyView.
The study demonstrates that dip coating at lower speeds significantly enhances the thermoelectric performance of P3HT by improving electrical conductivity. Contrary to expectations, this improvement is seemingly not due to polymer alignment but rather to better structural order achieved during slower solvent evaporation at lower dip coating speeds ...
Morteza Shokrani   +2 more
wiley   +1 more source

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