Results 191 to 200 of about 159,186 (304)

Nicotinamide Riboside Attenuates Cisplatin-Induced Hepatorenal Toxicity Through Restoration of NAD⁺ Homeostasis and Nrf2/NQO1-Dependent Antioxidant Signaling. [PDF]

Cells
Albahadly WKY, Rasool MI, Al-Saedi HFS, Al-Kareem ZA, Hasan SA, Sahib MA, ALtrufi MH.   +6 more
europepmc   +1 more source

Nicotinic acid starvation sensitizes nicotinate phosphoribosyltransferase-expressing tumors to nicotinamide phosphoribosyltransferase inhibition. [PDF]

Signal Transduct Target Ther
Ghanem MS, Ravera S, Benelli R, Nahimana A, Piacente F, Caffa I, Nencioni A.   +6 more
europepmc   +1 more source

Narrative review of intravenous NAD⁺ and NAD⁺ precursors in wellness and translational medicine. [PDF]

Front Aging
Alangari A, Arif J, Al Qureshah F, Alkhodairy F.   +3 more
europepmc   +1 more source

Nicotinamide Supplementation in Glaucoma: A Systematic Review of Human Studies. [PDF]

Nutrients
Giudiceandrea A, Cocuzza M, Gravina G, Silvestri V, Amore F, Sulfaro M, De Dominicis F, Bruzio S, Giudiceandrea E, Salgarello M, Cozzupoli GM, Savastano MC, Falsini B, Rizzo S, Salgarello T.   +14 more
europepmc   +1 more source

System‐Local Axes and Metabolic Reprogramming From Health to Response in House Dust Mite‐Specific Subcutaneous Immunotherapy for Allergic Rhinitis

iMetaMed, EarlyView.
This study delineated nasal‐plasma metabolic reprogramming in house dust mite‐allergic rhinitis (HDM‐AR) and subcutaneous immunotherapy (SCIT) response, showing compartment‐specific signatures dominated by nasal lipid‐redox and plasma nucleotide‐NAD+ axes and across the HC–HDM‐AR–SCIT response continuum, dual‑compartment metabolites exhibited ...
Bixing Fang, Fei Pan, Yachun Li, Yimeng Wang, Ze Wang, Zhiheng Huang, Ming Chen, Yun Li, Mengli Huang, Cheng Guo, Chubo Xie, Lina Dong, Yadong Gao, Zhuohang Yu   +13 more
wiley   +1 more source

Corrigendum to 'Nicotinamide riboside, pterostilbene and ibudilast protect motor neurons and extend survival in ALS mice'. [PDF]

Neurotherapeutics
Lo'pez-Blanch R, Salvador-Palmer R, Oriol-Caballo M, Moreno-Murciano P, Dellinger RW, Estrela JM, Obrador E.   +6 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Metabolic imaging for gamete and embryo assessment through advanced microscopy technologies: a novel avenue for artificial intelligence? [PDF]

Hum Reprod
Horta F, Sakkas D, Handley S, Xiong Y, Mihalas B, Deans R, Hart RJ, Gilchrist RB, Goldys EM.   +8 more
europepmc   +1 more source

The DIKW of Transcriptomics in Ecotoxicology: Extracting Information, Knowledge, and Wisdom From Big Data

Environmental Toxicology and Chemistry, EarlyView.
Jessica A. Head, Jessica D. Ewald, Niladri Basu   +2 more
wiley   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source