Results 191 to 200 of about 125,589 (257)

Nicotinamide for Skin Cancer Chemoprevention: The Jury Was Out and Still is. [PDF]

Am J Clin Dermatol
Tan E, Williams HC.
europepmc   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

Small, EarlyView.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Metabolic pathways linked to sarcopenia in the Bushehr Elderly Health Program: kynurenine, nicotinamide, B-vitamins, and sulfur amino acids. [PDF]

BMC Geriatr
Balajam NZ, Dehghanbanadaki H, Heshmat R, Mardani-Fard HA, Kasaeian A, Majidi Z, Bandarian F, Fahimfar N, Farzadfar F, Ostovar A, Nabipour I, Razi F, Shafiee G.   +12 more
europepmc   +1 more source

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

Deficiency of the NAD(P)HX metabolic repair system: a treatable mitochondrial disease. [PDF]

Orphanet J Rare Dis
Xu C, Jin H, Li J, Liu Z, Zhang W, Zhou J, Duan R, Liu Y, Song M, Zhang Z, Li T, Shen D, Zou Y, Wang J, Li H, Jiang H, Fang F.   +16 more
europepmc   +1 more source

Rotenone Induces Morphological Damage and Reduction in Catecholamine Levels in the Central Nervous System of the Ascidian Styela plicata

Environmental Toxicology, EarlyView.
ABSTRACT Ascidians are invertebrates that occupy a key phylogenetic position as a sister group of the vertebrates. The organization of their central nervous system (CNS), with cortex and medulla, indicates a plesiomorphic character of the gray and white matter of vertebrates, making this group of animals useful for studies of neurodegenerative events ...
Andressa de Abreu Mello, Carlos Augusto Borges de Andrade Gomes, Rafaela Rocha dos Santos, Cintia Monteiro de Barros, Silvana Allodi   +4 more
wiley   +1 more source

Mitochondrial Resilience in Glaucoma: Targeting NAD⁺ Metabolism and Oxidative Stress in Retinal Ganglion Cell Degeneration with Nicotinamide Riboside and Berberine: Preliminary Clinical Evidence. [PDF]

Diseases
Visalli F, Cappellani F, Gagliano G, Spinello A, Avitabile A, Cannizzaro L, Capobianco M, Gagliano C, Zeppieri M.   +8 more
europepmc   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source