Results 191 to 200 of about 126,234 (257)

Introgressed Brassica napus × Sinapis alba enhance resistance to the crucifer flea beetle (Phyllotreta cruciferae)

Pest Management Science, EarlyView.
This study demonstrates that Brassica napus lines with Sinapis alba introgressions enhanced resistance against Phyllotreta cruciferae, resulting in reduced feeding damage and improved seedling physiological performance. The introgressed lines showed strong potential as genetic resources for developing more resilient and sustainable canola varieties ...
Aziz Ullah, Altaf Hussain, Vicky Roslinsky, Sally L. Vail, Boyd A. Mori   +4 more
wiley   +1 more source

Polymorphism engineering of mefenamic acid for enhanced pharmacokinetic performance. [PDF]

EXCLI J
Prasher P, Sharma M.
europepmc   +1 more source

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

Phytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li, Yang‐Chi‐Dung Lin, Hsi‐Yuan Huang, Jihang Chen, Huali Zuo, Yun Tang, Hsien‐Da Huang   +6 more
wiley   +1 more source

Metabolic pathways linked to sarcopenia in the Bushehr Elderly Health Program: kynurenine, nicotinamide, B-vitamins, and sulfur amino acids. [PDF]

BMC Geriatr
Balajam NZ, Dehghanbanadaki H, Heshmat R, Mardani-Fard HA, Kasaeian A, Majidi Z, Bandarian F, Fahimfar N, Farzadfar F, Ostovar A, Nabipour I, Razi F, Shafiee G.   +12 more
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Recognition and confirmation of key genes associated with nicotinamide metabolism in acute myocardial infarction. [PDF]

Hereditas
Qu N, Bai F, Lan J.
europepmc   +1 more source

Photo‐responsive carbon dots for pyroptosis‐mediated anti‐tumor application

Responsive Materials, EarlyView.
Photo‐responsive CDs generate ROS to induce tumor cell pyroptosis, thereby stimulating antitumor immunity. Abstract Pyroptosis refers to a kind of lytic programmed cell death, characterized by the release of pro‐inflammatory cytokines during the process. Owing to its immune response stimulation ability, pyroptosis has garnered considerable attention in
Lingyun Li, Xue Wu, Zekun Yan, Jun Wu, Caishi Huang, Songnan Qu   +5 more
wiley   +1 more source

Injectable Zein‐Based Photothermal Composite Hydrogel Enhances Osteoporotic Tendon–Bone Healing

Small Methods, EarlyView.
Schematic illustration of the Zein‐based, dopamine‐grafted, niacin‐loaded carbon nanosphere (ZDC) composite hydrogel for enhancing healing of osteoporotic rotator cuff tears. This electron beam‐modified composite hydrogel is designed for NIR‐responsive release of niacin, which alleviates inflammation, promotes angiogenesis, and facilitates the ...
Kai Ye, Peng Ding, Zhenyou Dong, Wenyan Shi, Longxiang Shen, Xianyou Zheng   +5 more
wiley   +1 more source

Rotenone Induces Morphological Damage and Reduction in Catecholamine Levels in the Central Nervous System of the Ascidian Styela plicata

Environmental Toxicology, EarlyView.
ABSTRACT Ascidians are invertebrates that occupy a key phylogenetic position as a sister group of the vertebrates. The organization of their central nervous system (CNS), with cortex and medulla, indicates a plesiomorphic character of the gray and white matter of vertebrates, making this group of animals useful for studies of neurodegenerative events ...
Andressa de Abreu Mello, Carlos Augusto Borges de Andrade Gomes, Rafaela Rocha dos Santos, Cintia Monteiro de Barros, Silvana Allodi   +4 more
wiley   +1 more source

Nicotinamide for Skin Cancer Chemoprevention: The Jury Was Out and Still is. [PDF]

Am J Clin Dermatol
Tan E, Williams HC.
europepmc   +1 more source