Results 181 to 190 of about 222,121 (295)

Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression: The EPISODE Randomized Clinical Trial.

JAMA Psychiatry
Mertens LJ, Koslowski M, Betzler F, Brand M, Evens R, Kärtner L, Jungaberle A, Jungaberle H, Majic T, Schmitz CN, Ströhle A, Scharf D, Spangemacher M, Wolff M, Assadi Z, Bahri S, Becher L, Färber LV, Kirchen N, Kulakova E, Kunz L, Meijer A, Rohrmoser B, Wellek S, Berger MM, Gründer G.   +25 more
europepmc   +1 more source

Vitamins and nutraceuticals in glaucoma research. [PDF]

Eur J Ophthalmol
Hui F, Williams PA.
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

The NAD-brain pharmacokinetic study of NAD augmentation in blood and brain using oral precursor supplementation. [PDF]

iScience
Berven H, Svensen M, Eikeland H, Tvedten N, Sheard EV, Af Geijerstam SA, Søgnen M, McCann A, Arnsten L, Årseth O, Skjeie V, Hjellbrekke A, Skeie GO, Torres Cleuren YN, Nido GS, Haugarvoll K, Riemer F, Tzoulis C, Dölle C.   +18 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

The NAD salvage pathway enzyme NMNAT-C sustains dark-phase NAD+ homeostasis in cyanobacteria. [PDF]

Plant Physiol
Zhang F, Zhang H, Wang P, Qi Y, Li H, Zhu L, Huang G, Xia Y, Cai Z.   +8 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Chemoprevention in Skin Cancer: What Advice? [PDF]

Cancers (Basel)
Ortiz-Brugués A, Orte Cano C, Corbella L, Alamon-Reig F, Martí-Martí I, Ayguasanosa-Avila M, Hernández-Santacana M, Giavedoni P, Aguilera P, Carrera C.   +9 more
europepmc   +1 more source

Nicotinamide Phosphoribosyltransferase [PDF]

, 2020
openaire   +1 more source

Half a Century of Per‐ and Polyfluoroalkyl Substances in Northern Gannet Eggs: Impact of Regulations

Journal of Applied Toxicology, EarlyView.
ABSTRACT Per‐ and polyfluoroalkyl substances (PFAS), known as “forever chemicals”, are persistent organic pollutants that have been widely used in the industry across the globe for many decades. Their chemical stability, bioaccumulation, and toxicity pose major environmental and health risks. This study examines temporal trends in the concentrations of
Anaïs Fournier, Anaïs Kerric, Raphaël A. Lavoie   +2 more
wiley   +1 more source