Results 241 to 250 of about 132,023 (311)

NAD⁺ depletion drives age-related monocyte hyperinflammation after stroke and is reversed by nicotinamide riboside. [PDF]

J Neuroinflammation
Cabrera M, Eastman B, Ennerfelt H, Alsaadi AI, Alexandrova L, Ay YA, Huang J, Wang Q, Blacher E, McReynolds MR, Andreasson KI, Iweka CA.   +11 more
europepmc   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Nicotinamide Attenuates Complement and Coagulation Pathways and Resultant Renal Fibrosis. [PDF]

FASEB J
Kin S, Oe Y, Obara T, Sato E, Takahashi N, Miyazaki M, Tanaka T.   +6 more
europepmc   +1 more source

Reduction of NAD and NMN on mineral surfaces with H₂ reveals a functional role for the AMP moiety in a prebiotic context. [PDF]

Commun Chem
Henriques Pereira DP, Xie X, Stewart SV, Subrati Z, Beyazay T, Paczia N, Belz J, Volz K, Erastova V, Tüysüz H, Preiner M.   +10 more
europepmc   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Dysregulation of Niacin-Derived NAD⁺ Salvage Pathway Markers (CD38, NAMPT, SIRT1) Across Albuminuria Stages in Type 2 Diabetes. [PDF]

Medicina (Kaunas)
Huwaimel B, Alqarni S, Abouzied AS, Alghubayshi A, Alotaibi T, Elshafei A, Yassien M, Nasr M, Khidr EG.   +8 more
europepmc   +1 more source

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source

Nicotinamide Mononucleotide Enhances Boar Sperm Quality via Maintaining Mitochondrial Function During Liquid Storage. [PDF]

Animals (Basel)
Liu Y, Zhang H, Meng Q, Min L, Zhang M, Adetunji AO, Li W, Zhu Z.   +7 more
europepmc   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Structural evolution of the selectivity clamp confers ADPR-PP specificity in Namat, a phage nicotinamide ADP-ribose transferase. [PDF]

Nucleic Acids Res
Lan M, Xu L, Han Y, Cui T, Qiao Z, Teng YB, Wang N, Bao H.   +7 more
europepmc   +1 more source