Results 71 to 80 of about 155,595 (297)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Nicotinamide Administration Improves Remyelination after Stroke [PDF]
, 2017 Aims. Stroke is a leading cause of morbidity and mortality. This study aimed to determine whether nicotinamide administration could improve remyelination after stroke and reveal the underlying mechanism. Methods.
Ying Luan +6 more
core +1 more source
Effects of Nicotinamide on Cervical Cancer-Derived Fibroblasts: Evidence for Therapeutic Potential
Cancer Management and Research, 2020 Reem N Hassan,* Hualei Luo,* Weiying Jiang Department of Medical Genetics, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, Guangdong 510080, People’s Republic of China*These authors contributed equally to this workCorrespondence ...
Hassan RN, Luo H, Jiang W
doaj
Marine Drugs, 2018 Fungi usually contain gene clusters that are silent or cryptic under normal laboratory culture conditions. These cryptic genes could be expressed for a wide variety of bioactive compounds. One of the recent approaches to induce production of such cryptic
Seham S. El-Hawary +8 more
doaj +1 more source
Self‐Assembled Hybrid Cell‐Enzyme Materials for Gas‐Powered Biocatalysis
Advanced Functional Materials, EarlyView.Integrating living cells with programmable enzyme networks enables hybrid materials that convert gaseous feedstocks into chemical reducing power. These gas‐powered catalytic beads operate as modular, recyclable platforms for adaptive biocatalysis and sustainable synthesis.
Marius Stoeckle +2 more
wiley +1 more source
The role of nicotinamide in acne treatment [PDF]
, 2017 Safe and effective treatment options for acne vulgaris are needed to address side effects and increasing rates of antibiotic resistance from current treatments.
Frances M. Walocko +13 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
, 2008 Objective: Insulin resistance can modulate progression to type 1 diabetes in individuals with ongoing islet autoimmunity. We wanted to see whether measures of insulin resistance improved risk assessment in ICA positive relatives when added to other ...
Bingley, PJ +3 more
core +1 more source
Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy [PDF]
, 2018 Nicotinamide N-methyl-transferase (NNMT) is an essential contributor to various metabolic and epigenetic processes, including the regulating of aging, cellular stress response, and body weight gain. Epidemiological studies show that NNMT is a risk factor
J. Alex Parker (148331) +3 more
core +1 more source
Pharmaceutical Biology, 2017 Context: Metformin attenuates type-2 diabetes mellitus (T2DM)-induced hepatic dysfunction and altered PI3K/Akt/GLUT-4 signalling in experimental studies.
Debapriya Garabadu, Sairam Krishnamurthy
doaj +1 more source