Results 91 to 100 of about 159,186 (304)
Creation of Bioorthogonal Redox Systems Depending on Nicotinamide Flucytosine Dinucleotide
, 2011 Creation of Bioorthogonal Redox Systems Depending on Nicotinamide Flucytosine DinucleotideMany enzymes catalyzing biological redox chemistry depend on the omnipresent cofactor, nicotinamide adenine dinucleotide (NAD).
Wang, Jinxia +7 more
core +1 more source
Engineering an Artificial Metalloenzyme for Efficient Photo‐Enzymatic CO2 Conversion
Advanced Science, EarlyView.We built a light‐driven artificial metalloenzyme by covalently conjugating formate dehydrogenase (FDH) with a tailored rhodium complex (Rh‐L6) to overcome spatial‐separation‐limited electron transfer. This integration boosts NADH regeneration and CO2 conversion, giving 2.31‐fold higher formate yield than physical mixtures, due to a narrowed bandgap and
Mengxue Kang +6 more
wiley +1 more source
Nicotinamide adenine dinucleotide (reduced)
, 2017 Inelastic Neutron Scattering spectrum of Nicotinamide adenine dinucleotide (reduced), C₆H₆N₂O, measured on the TFXA ...
R. E. Hester, University of York
core +1 more source
, 2022 Supplemental material, Supplementary Material 1, for Effect of Nicotinamide in Skin Cancer and Actinic Keratoses Chemoprophylaxis, and Adverse Effects Related to Nicotinamide: A Systematic Review and Meta-Analysis by Laurence Mainville, Anne-Sophie ...
Paul R. Fortin (4694209) +2 more
core +1 more source
AARS2‐SIRT5‐Driven DLD K445 Lactylation Promotes Cuproptosis Resistance in Glioblastoma Stem Cells
Advanced Science, EarlyView.Lactylation of DLD at K445 by AARS2 suppresses PDH complex activity and reduces DLAT lipoylation, thereby conferring cuproptosis resistance in glioblastoma stem cells. SIRT5‐mediated delactylation restores PDH function and enhances cuproptosis sensitivity.
Mingtian Ding +12 more
wiley +1 more source
Amyotrophic lateral sclerosis and intestinal microbiota—toward establishing cause and effect
Gut Microbes, 2020 The intestinal microbiota may be involved, through metabolic gut–brain interactions, in a variety of neurological conditions. In this addendum, we summarize the findings of our recent study investigating the potentially modulatory influence of the ...
Marc Gotkine +2 more
doaj +1 more source
Nicotinamide concentrations for microfluidic flow cell testing.
, 2019 Nicotinamide concentrations for microfluidic flow cell testing.
S. D. R. Christie (8038775) +3 more
core +1 more source
Advanced Science, EarlyView.Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li +9 more
wiley +1 more source
Nicotinamide Inhibition against SIRT5 Variants and SIRT1.
, 2016 Nicotinamide Inhibition against SIRT5 Variants and SIRT1.
Manas Haldar (1345884) +3 more
core +1 more source
Advanced Science, EarlyView.Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong +13 more
wiley +1 more source