Results 81 to 90 of about 256,874 (388)

Topical nicotinamide in combination with calcipotriol for the treatment of mild to moderate psoriasis: A double-blind, randomized, comparative study

Advanced Biomedical Research, 2013
Background: Current treatment strategies of psoriasis are not completely satisfactorily. By inhibiting inflammatory cytokines, nicotinamide may enhance the effects of current topical treatments.
Amir Hossein Siadat, Fariba Iraji, Mehdi Khodadadi, Maryam Kalateh Jary   +3 more
doaj   +1 more source

Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults

Scientific Reports, 2019
Nicotinamide riboside (NR) is a newly discovered nicotinamide adenine dinucleotide (NAD+) precursor vitamin. A crystal form of NR chloride termed NIAGEN is generally recognized as safe (GRAS) for use in foods and the subject of two New Dietary Ingredient
D. Conze, C. Brenner, C. Kruger
semanticscholar   +1 more source

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang, Yeoung Eun Choi, Song Yi Lee, Mrinmoy Karmakar, Qiaojun Hao, Junmin Lee, Hyun‐Jong Cho   +6 more
wiley   +1 more source

The role of nicotinamide adenine dinucleotide salvage enzymes in cardioprotection

Polish Journal of Thoracic and Cardiovascular Surgery
The increasing trend of cardiac diseases is becoming a major threat globally. Cardiac activities are based on integrated action potential through electronic flux changes within intra- and extracellular molecular activities.
Fazle Kibria, Sudip Kumar Das, Md Sahidul Arefin   +2 more
doaj   +1 more source

Dual Antimelanogenic Effect of Nicotinamide-Stabilized Phloretin Nanocrystals in Larval Zebrafish

Pharmaceutics, 2022
Melanin is a kind of dark insoluble pigment that can cause pigmentation and free-radical clearance, inducing melasma, freckles, and chloasma, affecting the quality of life of patients. Due to poor water solubility and low safety, the absorption of poorly
Yixuan Li, Hong Xiang, Xinyue Xue, Yilan Chen, Zhiyuan He, Zhongrui Yu, Li Zhang, Xiaoqing Miao   +7 more
doaj   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Nicotinamide Supplementation Attenuates Renal Interstitial Fibrosis via Boosting the Activity of Sirtuins

Kidney Diseases, 2021
Background: Progressive tubulointerstitial fibrosis (TIF) is the final common pathway leading to ESRD. There is an urgent need to develop effective approaches slowing the progression of TIF.
Xin Zhen, Shaowu Zhang, Feifei Xie, Miaomiao Zhou, Zheng Hu, Fengxin Zhu, Jing Nie   +6 more
doaj   +1 more source

Age- and AD-related redox state of NADH in subcellular compartments by fluorescence lifetime imaging microscopy. [PDF]

, 2019
Nicotinamide adenine dinucleotide (reduced form: NADH) serves as a vital redox-energy currency for reduction-oxidation homeostasis and fulfilling energetic demands.
Brewer, Gregory J, Digman, Michelle A, Dong, Yue   +2 more
core   +1 more source

P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules [PDF]

, 2019
A set of dual functional small molecules (DFSMs) containing different amino acids has been synthesized and employed together with three different variants of the cytochrome P450 monooxygenase P450BM3 from Bacillus megaterium in H2O2-dependent oxidation
Girhard, Marco, Gonzalo Calvo, Gonzalo de, Hollmann, Frank, Tieves, Florian, Urlacher, Vlada B., Willot, Sébastien Jean-Paul   +5 more
core   +1 more source

From Exciton Dynamics to Cell Fate: A Carbon Dot Based NIR Photocatalytic Platform for Pyroptosis via Self‐Trapped Excitons

Advanced Functional Materials, EarlyView.
A facile and effective method to boost NIR light induced photocatalysis based on nontoxic NIR emissive carbon dots (nir‐CDs) via Self‐trapped excitons, showing that both O2− • and •OH can be generated from nir‐CDs under NIR laser irradiation. Abstract Near‐infrared (NIR) light‐triggered photocatalytic therapy remains a critical challenge in efficient ...
Qingcheng Wang, Quansheng Cheng, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Ruifeng Zheng, Shi Chen, Guichuan Xing, Songnan Qu   +8 more
wiley   +1 more source