Results 121 to 130 of about 134,103 (347)

Model based study of autothermal thermophilic aerobic digestion (ATAD) processes : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Engineering and Automation of Massey University [PDF]

, 2000
An Autothermal Thermophilic Aerobic Digestion process, or ATAD process, is a relatively new sewage sludge treatment process. The ATAD process has been developed for the disinfection and stabilisation of sewage sludge, which is a by-product of wastewater ...
Fryer, Barry
core  

Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ Damage

Advanced Science, EarlyView.
Src reduces neutrophil extracellular traps (NETs) generation and resolves acute organ damage. Src directly activates RAF1 by regulating phosphorylation at the Ser 621 site and mediates the RAF/MEK/ERK pathway, thereby affecting the intracellular ROS production. Alternatively, Src activates the RAF1/MEK/ERK pathway by mediating PKC phosphorylation.
Guotao Lu, Fei Han, Yaodong Wang, Chenchen Yuan, Qingtian Zhu, Tianqi Xia, Lin Chen, Xiaowu Dong, Yanbing Ding, Weiming Xiao, Yuyan Zhang, Jiajia Pan, Hongwei Xu, Weiwei Chen, Bo Tu, Wei Li, Fei Wang, Weijuan Gong, Lianghao Hu   +18 more
wiley   +1 more source

Exploring the Therapeutic Potential of Nicotinamide Mononucleotide: A Review of Safety and Efficacy with Emphasis on Diabetes

Quality in Sport
Introduction: Nicotinamide mononucleotide (NMN) is a supplement that can boost nicotinamide adenine dinucleotide (NAD+) levels in the body, which is crucial for maintaining energy balance and stress response. Declining NAD+ levels with age contribute to
Hubert Gugulski, Michał Andrzej Kozicz, Szymon Rudawski, Łukasz Wójcik, Magdalena Zięba, Ilona Jastrzębska, Michał Bado, Patrycja Nowoświat, Paulina Cuper, Krzysztof Bilecki   +9 more
doaj   +1 more source

Biofilm development in a fluidized bed bioreactor for aerobic phenol degradation : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Biotechnology and Bioprocess Engineering at Massey University [PDF]

, 1993
The main objective of this thesis was to follow the biofilm development during start-up of a fluidized bed biorcactor with the help of digital image processing.
Maushake, Kirsten
core  

ROS‐Responsive Hydrogel for Localized Delivery of Nampt and Stat3 Inhibitors Exhibits Synergistic Antitumor Effects in Colorectal Cancer Through Ferroptosis Induction and Immune Microenvironment Remodeling

Advanced Science, EarlyView.
In this study, ferroptosis in colorectal cancer cells is induced by FK866 through the NAD⁺/STAT3/GPX4 pathway. To minimize systemic toxicity, a reactive oxygen species (ROS)‐responsive hydrogel is developed to co‐deliver FK866 and C188‐9, resulting in synergistic and localized antitumor effects.
Chenyang Ye, Mi Mi, Saimeng Shi, Lina Qi, Shanshan Weng, Lu Wang, Yier Lu, Chao Chen, Yinuo Tan, Mengyuan Yang, Cheng Guo, Rui Bai, Xuefeng Fang, Ji Wang, Ying Yuan   +14 more
wiley   +1 more source

Steady-State Concentrations of Glucose-6-Phosphate, 6-Phosphogluconate, and Reduced Nicotinamide Adenine Dinucleotide Phosphate in Strains of Escherichia coli Sensitive and Resistant to Catabolite Repression [PDF]

, 1969
Abraham W. Hsie, H.V. Rickenberg, Demoy W. Schulz, Wolff M. Kirsch   +3 more
openalex   +1 more source

Heme/NADH Mimics Co‐Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion

Advanced Science, EarlyView.
Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma, Yihao Zhang, Junkai Cai, Baotong Ding, Yang Jiao, Chunying Duan   +5 more
wiley   +1 more source

Diphenyleneiodonium chloride synergizes with diazoxide to enhance protection against amyloid β induced neurotoxicity

Journal of Integrative Neuroscience, 2019
We examined synergistic effects of inhibiting reactive oxygen species generated from the mitochondria and from nicotinamide adenine dinucleotide phosphate oxidase on neurotoxicity. Primary hippocampal neurons were exposed to amyloid β, and the cells were
Qingxi Fu, Naiyong Gao, Fengyuan Che, Guangyin Xu, Hongxing Han, Quanping Su, Guozhao Ma   +6 more
doaj   +1 more source

Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts. [PDF]

, 2019
Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD+) are critical for maintaining redox homeostasis. Aging as
Brewer, Gregory J, Digman, Michelle A, Dong, Yue, Sameni, Sara   +3 more
core  

Xylose Metabolism Perturbation in Yarrowia lipolytica for Efficient Succinic Acid Bioproduction from Lignocellulosic Biomass

Advanced Science, EarlyView.
This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong, Changyu Shang, Jinhong Gu, Huilin Tao, Xuemei Lu, Jin Hou, Zhiyong Cui, Qingsheng Qi   +7 more
wiley   +1 more source