Results 61 to 70 of about 6,777 (132)

SIRT1 selectively exerts the metabolic protective effects of hepatocyte nicotinamide phosphoribosyltransferase. [PDF]

Nat Commun, 2022
Higgins CB, Mayer AL, Zhang Y, Franczyk M, Ballentine S, Yoshino J, DeBosch BJ.   +6 more
europepmc   +1 more source

Nicotinamide phosphoribosyltransferase (NamPRT; NAMPT) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity. [PDF]

Cell Res, 2022
Yao H, Liu M, Wang L, Zu Y, Wu C, Li C, Zhang R, Lu H, Li F, Xi S, Chen S, Gu X, Liu T, Cai J, Wang S, Yang M, Xing GG, Xiong W, Hua L, Tang Y, Wang G.   +20 more
europepmc   +1 more source

Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4. [PDF]

J Biol Chem, 2022
Gasparrini M, Mazzola F, Cuccioloni M, Sorci L, Audrito V, Zamporlini F, Fortunato C, Amici A, Cianci M, Deaglio S, Angeletti M, Raffaelli N.   +11 more
europepmc   +1 more source

Nicotinamide Phosphoribosyltransferase as a Key Molecule of the Aging/Senescence Process. [PDF]

Int J Mol Sci, 2021
Khaidizar FD, Bessho Y, Nakahata Y.
europepmc   +1 more source

Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4. [PDF]

iScience, 2022
Colombo G, Travelli C, Porta C, Genazzani AA.   +3 more
europepmc   +1 more source

Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy. [PDF]

Cell Death Dis, 2022
Deng Y, Duan R, Ding W, Gu Q, Liu M, Zhou J, Sun J, Zhu J.   +7 more
europepmc   +1 more source

Nicotinamide phosphoribosyltransferase inhibitors, design, preparation and SAR.

, 2013
Existing pharmacological inhibitors for nicotinamide phosphoribosyltransferase (NAMPT) are promising therapeutics for treating cancer. Using medicinal and computational chemistry methods, the structure-activity relationship for novel classes of NAMPT inhibitors is described and compounds optimized. Compounds are designed inspired by the NAMPT inhibitor
Christensen, Mette Knak, Erichsen, Kamille Dumong, Olesen, Uffe Hogh, Tjørnelund, Jette, Fristrup, Peter, Thougaard, Annemette, Nielsen, Søren Jensby, Sehested, Maxwell, Jensen, Peter B., Loza, Einars, Kalvinsh, Ivars, Garten, Antje, Kiess, Wieland, Bjorkling, Fredrik   +13 more
openaire   +1 more source

Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy. [PDF]

J Med Chem
Galli U, Moro M, Balestrero FC, Colombo G, Koten M, Roncaglio B, Genazzani AA, Aprile S, Massarotti A, Orsomando G, Pirali T, Grolla AA.   +11 more
europepmc   +1 more source

Circular RNA triple functional domain promotes osteoarthritis' development by modulating the microRNA-136-5p/Nicotinamide phosphoribosyltransferase axis. [PDF]

Bioengineered, 2022
Yang J, Li Q, Wang T, Lv K.
europepmc   +1 more source