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Nicotine delivery and cigarette equivalents from vaping a JUULpod
With patented nicotine salt technology, JUUL dominates the e-cigarette market. We reviewed studies of JUUL’s nicotine pharmacokinetic profile and studies quantifying nicotine in a JUULpod, emitted in the aerosol and absorbed by users.
J. Prochaska, Erin A. Vogel, N. Benowitz
semanticscholar +1 more source
Key Points Question Does exposure to electronic cigarettes (e-cigarettes) in salt vs free-base nicotine formulations improve the appeal and sensory experience of vaping?
A. Leventhal +9 more
semanticscholar +1 more source
Synthetic nicotine has arrived
The introduction of a new product line of the popular disposable electronic cigarette brand Puffbar, advertised as containing synthetic nicotine, has drawn attention to the increasing use of synthetic nicotine in marketed products and its uncertain ...
S. Jordt
semanticscholar +1 more source
Characterization of Total and Unprotonated (Free) Nicotine Content of Nicotine Pouch Products.
INTRODUCTION Nicotine pouch products, oral smokeless products that contain nicotine but no tobacco leaf material, have recently entered the US marketplace.
S. Stanfill +9 more
semanticscholar +1 more source
An aversive abstinence syndrome manifests 4-24 h following cessation of chronic use of nicotine-containing products. Symptoms peak on approximately the 3rd day and taper off over the course of the following 3-4 weeks.
I. McLaughlin, J. Dani, M. De Biasi
semanticscholar +1 more source
A Randomized Trial of E‐Cigarettes versus Nicotine‐Replacement Therapy
Background E‐cigarettes are commonly used in attempts to stop smoking, but evidence is limited regarding their effectiveness as compared with that of nicotine products approved as smoking‐cessation treatments.
P. Hajek +13 more
semanticscholar +1 more source
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis
Cigarette smoking is a major risk factor for atherosclerosis and other cardiovascular diseases. Increasing evidence has demonstrated that nicotine impairs the cardiovascular system by targeting vascular endothelial cells, but the underlying mechanisms ...
Xian-xian Wu +13 more
semanticscholar +1 more source
Stress-induced reinstatement of nicotine preference requires dynorphin/kappa opioid activity in the basolateral amygdala [PDF]
UNLABELLED: The dynorphin (DYN)/kappa-opioid receptor (KOR) system plays a conserved role in stress-induced reinstatement of drug seeking for prototypical substances of abuse.
Bruchas, Michael R +4 more
core +2 more sources
Nicotine replacement therapy versus control for smoking cessation.
BACKGROUND Nicotine replacement therapy (NRT) aims to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence ...
J. Hartmann-Boyce +4 more
semanticscholar +1 more source
The Effects of Nicotine on Development
Recently, there has been a significant increase in the use of noncombustible nicotine–containing products, including electronic cigarettes (e-cigarettes).
S. McGrath-Morrow +7 more
semanticscholar +1 more source

