Results 1 to 10 of about 469,346 (331)

Nicotine delivery and cigarette equivalents from vaping a JUULpod

open access: yesTobacco Control, 2021
With patented nicotine salt technology, JUUL dominates the e-cigarette market. We reviewed studies of JUUL’s nicotine pharmacokinetic profile and studies quantifying nicotine in a JUULpod, emitted in the aerosol and absorbed by users.
J. Prochaska, Erin A. Vogel, N. Benowitz
semanticscholar   +1 more source

Effect of Exposure to e-Cigarettes With Salt vs Free-Base Nicotine on the Appeal and Sensory Experience of Vaping

open access: yesJAMA Network Open, 2021
Key Points Question Does exposure to electronic cigarettes (e-cigarettes) in salt vs free-base nicotine formulations improve the appeal and sensory experience of vaping?
A. Leventhal   +9 more
semanticscholar   +1 more source

Synthetic nicotine has arrived

open access: yesTobacco Control, 2021
The introduction of a new product line of the popular disposable electronic cigarette brand Puffbar, advertised as containing synthetic nicotine, has drawn attention to the increasing use of synthetic nicotine in marketed products and its uncertain ...
S. Jordt
semanticscholar   +1 more source

Characterization of Total and Unprotonated (Free) Nicotine Content of Nicotine Pouch Products.

open access: yesNicotine & Tobacco Research, 2021
INTRODUCTION Nicotine pouch products, oral smokeless products that contain nicotine but no tobacco leaf material, have recently entered the US marketplace.
S. Stanfill   +9 more
semanticscholar   +1 more source

Nicotine withdrawal.

open access: yesCurrent topics in behavioral neurosciences, 2020
An aversive abstinence syndrome manifests 4-24 h following cessation of chronic use of nicotine-containing products. Symptoms peak on approximately the 3rd day and taper off over the course of the following 3-4 weeks.
I. McLaughlin, J. Dani, M. De Biasi
semanticscholar   +1 more source

A Randomized Trial of E‐Cigarettes versus Nicotine‐Replacement Therapy

open access: yesNew England Journal of Medicine, 2019
Background E‐cigarettes are commonly used in attempts to stop smoking, but evidence is limited regarding their effectiveness as compared with that of nicotine products approved as smoking‐cessation treatments.
P. Hajek   +13 more
semanticscholar   +1 more source

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

open access: yesCell Death and Disease, 2018
Cigarette smoking is a major risk factor for atherosclerosis and other cardiovascular diseases. Increasing evidence has demonstrated that nicotine impairs the cardiovascular system by targeting vascular endothelial cells, but the underlying mechanisms ...
Xian-xian Wu   +13 more
semanticscholar   +1 more source

Stress-induced reinstatement of nicotine preference requires dynorphin/kappa opioid activity in the basolateral amygdala [PDF]

open access: yes, 2016
UNLABELLED: The dynorphin (DYN)/kappa-opioid receptor (KOR) system plays a conserved role in stress-induced reinstatement of drug seeking for prototypical substances of abuse.
Bruchas, Michael R   +4 more
core   +2 more sources

Nicotine replacement therapy versus control for smoking cessation.

open access: yesCochrane Database of Systematic Reviews, 2018
BACKGROUND Nicotine replacement therapy (NRT) aims to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence ...
J. Hartmann-Boyce   +4 more
semanticscholar   +1 more source

The Effects of Nicotine on Development

open access: yesPediatrics, 2020
Recently, there has been a significant increase in the use of noncombustible nicotine–containing products, including electronic cigarettes (e-cigarettes).
S. McGrath-Morrow   +7 more
semanticscholar   +1 more source

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