Synthetic nicotine e-liquids sold in US online vape shops
Synthetic nicotine (relative to tobacco-derived, or “natural” nicotine) is an emerging feature of e-cigarettes including e-liquids in the online marketplace. This study investigated a total of 11,161 unique nicotine e-liquids sold in online stores in the
Shaoying Ma+3 more
doaj
Direct genetic effects and their estimation from matched case-control data [PDF]
In genetic association studies, a single marker is often associated with multiple, correlated phenotypes (e.g., obesity and cardiovascular disease, or nicotine dependence and lung cancer). A pervasive question is then whether that marker has independent effects on all phenotypes. In this article, we address this question by assessing whether there is a
arxiv
Computational neuroanatomy and co-expression of genes in the adult mouse brain, analysis tools for the Allen Brain Atlas [PDF]
We review quantitative methods and software developed to analyze genome-scale, brain-wide spatially-mapped gene-expression data. We expose new methods based on the underlying high-dimensional geometry of voxel space and gene space, and on simulations of the distribution of co-expression networks of a given size.
arxiv
Tobacco-free nicotine pouches are new nicotine products for oral consumption. They can contain very high nicotine amounts that have not been addressed with clinical studies yet.
Nadja Mallock-Ohnesorg+14 more
doaj +1 more source
Nicotine delivery from the refill liquid to the aerosol via high-power e-cigarette device
To offer an enhanced and well-controlled nicotine delivery from the refill liquid to the aerosol is a key point to adequately satisfy nicotine cravings using electronic nicotine delivery systems (ENDS). A recent high-power ENDS, exhibiting higher aerosol
Nathalie Prévôt+5 more
doaj +1 more source
Cholesterol modulates acetylcholine receptor diffusion by tuning confinement sojourns and nanocluster stability [PDF]
Translational motion of neurotransmitter receptors is key for determining receptor number at the synapse and hence, synaptic efficacy. We combine live-cell STORM superresolution microscopy of nicotinic acetylcholine receptor (nAChR) with single-particle tracking, mean-squared displacement (MSD), turning angle, ergodicity, and clustering analyses to ...
arxiv
Comparative study of ethanol, caffeine and nicotine on behavior of albino rats [PDF]
David I. Macht, W. Bloom
openalex +1 more source
HPTLC assay of nicotine and cotinine in biological samples [PDF]
This study presents the development of a simple high-performance thin layer chromatography (HPTLC) method for the determination of nicotine and its metabolite cotinine in human plasma and urine.
Baconi, Daniela Luiza+6 more
core +1 more source
The Analgesia-Enhancing Component of\ud Ingested Amniotic Fluid Does Not Affect\ud Nicotine-Induced Antinociception in\ud Naltrexone-Treated Rats [PDF]
Ingestion of amniotic fluid and placenta by rats has been shown to enhance opioid-mediated antinociception but not affect the nonopioid-mediated antinociception produced by aspirin, suggesting spccificity for opioid-mediated processes.
Caggiula, Dr. A.R.+3 more
core
Is it the nicotine or the tobacco?
Recentyearshaveseenagrowingrecognitionthatproductregulationiscriticaltodealingeffectivelywiththetobaccoepidemic.Itisalsonowwidelyrecognizedthat,thoughitisthenicotinethatcausesdependence, tobacco products (which can becharacterized as particularly ‘dirty’ drug deliverydevices)areresponsibleforthevastmajorityofthedamage to health.
openaire +5 more sources