Results 141 to 150 of about 458,722 (380)
With the advent of nicotine replacement therapy, the consumption of the nicotine is on the rise. Nicotine is considered to be a safer alternative of tobacco. The IARC monograph has not included nicotine as a carcinogen.
A. Mishra+5 more
semanticscholar +1 more source
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière+13 more
wiley +1 more source
The destruction of isonicotinic acid hydrazide in the presence of haemin [PDF]
Adrien Albert, Charles W. Rees
openalex +1 more source
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside+5 more
wiley +1 more source
THE NICOTINE‐LIKE ACTIONS OF THE 3‐BROMO‐ AND 3:5‐DIBROMO‐PHENYL ETHERS OF CHOLINE (MBF AND DBF) [PDF]
N Ambache, P. A. Robertson
openalex +1 more source
Nicotine delivery to users from cigarettes and from different types of e-cigarettes
Delivering nicotine in the way smokers seek is likely to be the key factor in e-cigarette (EC) success in replacing cigarettes. We examined to what degree different types of EC mimic nicotine intake from cigarettes.
P. Hajek+4 more
semanticscholar +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah+9 more
wiley +1 more source
An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse. [PDF]
Tobacco use disorder is the leading cause of disease and preventable death worldwide, but current medications that are based on pharmacodynamics have low efficacy.
George, Olivier+4 more
core +1 more source