Results 141 to 150 of about 170,260 (319)

MicroRNA Regulation of nAChR Expression and Nicotine-Dependent Behavior in C. elegans

open access: yesCell Reports, 2017
Summary: Chronic exposure to nicotine upregulates nicotinic acetylcholine receptors (nAChRs), and such upregulation is critical for the development of nicotine dependence in humans and animal models.
Manish Rauthan   +6 more
doaj  

Research progress on the mechanisms of pain empathy

open access: yesIbrain, EarlyView.
This article is related to the graphical research progress of pain empathy, starting with the description of the pain matrix and mirror neurons. Based on the pain matrix and mirror neurons, pain empathy results from the combined action of brain regions such as the anterior cingulate cortex, insula, prefrontal cortex, and amygdala and regulatory ...
Shuangshuang Liu   +5 more
wiley   +1 more source

SERINE AND FORMALDEHYDE AS METABOLIC PRECURSORS FOR THE NICOTINE N-METHYL GROUP

open access: hybrid, 1955
Richard U. Byerrum   +3 more
openalex   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug–Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules   +4 more
wiley   +1 more source

THE STEREOSPECIFICITY OF NICOTINE [PDF]

open access: yesBritish Journal of Pharmacology and Chemotherapy, 1965
J. T. Hamilton, R. B. Barlow
openaire   +3 more sources

Multi‐cycle high‐throughput growth media optimization using batch Bayesian optimization

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND The optimization of growth media is a crucial step in enhancing microbial growth and product formation in industrial bioprocesses. While Design of Experiments (DoE) is widely used for this purpose, it has inherent limitations, particularly in capturing complex interactions between media components and managing the high number of ...
Frédéric M. Lapierre   +5 more
wiley   +1 more source

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