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The Effects of Nicotine on Development
Pediatrics, 2020 Recently, there has been a significant increase in the use of noncombustible nicotine–containing products, including electronic cigarettes (e-cigarettes).
S. McGrath-Morrow +7 more
semanticscholar +1 more source
Digital Health, 2023 Objective Varenicline is the most efficacious approved smoking cessation medication, making it one of the most cost-effective clinical interventions for reducing tobacco-related morbidity and mortality. Adhering to varenicline is strongly associated with
Nadia Minian +7 more
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Nicotine replacement therapy versus control for smoking cessation.
Cochrane Database of Systematic Reviews, 2018 BACKGROUND Nicotine replacement therapy (NRT) aims to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence ...
J. Hartmann-Boyce +4 more
semanticscholar +1 more source
Neuron, 2009 Both conscious and unconscious memory mechanisms contribute to the rewarding effects of nicotine and other drugs of abuse. In this issue of Neuron, Tang and Dani use in vivo measures of synaptic plasticity in freely moving mice to link nicotine-induced dopamine release in hippocampus to LTP induction and behavioral reinforcement.
openaire +3 more sources
Comparative cytotoxicity study of nicotine and cotinine on MRC-5 cell line [PDF]
, 2018 Nicotine has several health hazards regarding carcinogenic potential. It also imparts increased risk for respiratory, cardiovascular, and gastrointestinal disorders.
Baconi, Daniela Luiza +4 more
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Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis
Cell Death and Disease, 2018 Cigarette smoking is a major risk factor for atherosclerosis and other cardiovascular diseases. Increasing evidence has demonstrated that nicotine impairs the cardiovascular system by targeting vascular endothelial cells, but the underlying mechanisms ...
Xian-xian Wu +13 more
semanticscholar +1 more source
Frontiers in Neuroscience, 2023 Since their introduction in the United States and Europe in 2007, electronic cigarettes (E-Cigs) have become increasingly popular among smokers. Nicotine, a key component in both tobacco and e-cigarettes, can exist in two forms: nicotine-freebase (FBN ...
Pengfei Han +36 more
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New England Journal of Medicine, 1999 Nicotine maintains tobacco addiction. Nicotine acts on nicotinic cholinergic receptors, which demonstrate diversity in subunit structure, function, and distribution in the nervous system, mediating the multiple actions of nicotine described in tobacco users.
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Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine.
Journal of Clinical Investigation, 2019 Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular recreational tool among adolescents and adults. Although the use of ENDS is often promoted as a safer alternative to conventional cigarettes, few comprehensive studies ...
M. Madison +16 more
semanticscholar +1 more source