Results 21 to 30 of about 465,225 (381)
Nicotine replacement therapy versus control for smoking cessation.
Cochrane Database of Systematic Reviews, 2018 BACKGROUND Nicotine replacement therapy (NRT) aims to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence ...
J. Hartmann-Boyce +4 more
semanticscholar +1 more source
Neuron, 2009 Both conscious and unconscious memory mechanisms contribute to the rewarding effects of nicotine and other drugs of abuse. In this issue of Neuron, Tang and Dani use in vivo measures of synaptic plasticity in freely moving mice to link nicotine-induced dopamine release in hippocampus to LTP induction and behavioral reinforcement.
openaire +3 more sources
Comparative cytotoxicity study of nicotine and cotinine on MRC-5 cell line [PDF]
, 2018 Nicotine has several health hazards regarding carcinogenic potential. It also imparts increased risk for respiratory, cardiovascular, and gastrointestinal disorders.
Baconi, Daniela Luiza +4 more
core +4 more sources
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis
Cell Death and Disease, 2018 Cigarette smoking is a major risk factor for atherosclerosis and other cardiovascular diseases. Increasing evidence has demonstrated that nicotine impairs the cardiovascular system by targeting vascular endothelial cells, but the underlying mechanisms ...
Xian-xian Wu +13 more
semanticscholar +1 more source
New England Journal of Medicine, 1999 Nicotine maintains tobacco addiction. Nicotine acts on nicotinic cholinergic receptors, which demonstrate diversity in subunit structure, function, and distribution in the nervous system, mediating the multiple actions of nicotine described in tobacco users.
openaire +3 more sources
Frontiers in Neuroscience, 2023 Since their introduction in the United States and Europe in 2007, electronic cigarettes (E-Cigs) have become increasingly popular among smokers. Nicotine, a key component in both tobacco and e-cigarettes, can exist in two forms: nicotine-freebase (FBN ...
Pengfei Han +36 more
doaj +1 more source
Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine.
Journal of Clinical Investigation, 2019 Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular recreational tool among adolescents and adults. Although the use of ENDS is often promoted as a safer alternative to conventional cigarettes, few comprehensive studies ...
M. Madison +16 more
semanticscholar +1 more source
Nicotine strongly activates dendritic cell-mediated adaptive immunity - potential role for progression of atherosclerotic lesions [PDF]
, 2003 Background - Antigen-presenting cells (APCs) such as monocytes and dendritic cells (DCs) stimulate T-cell proliferation and activation in the course of adaptive immunity.
Aicher, A +5 more
core +1 more source
Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells [PDF]
, 2016 In addition to the T2R bitter taste receptors, neuronal nicotinic acetylcholine receptors (nAChRs) have recently been shown to be involved in the bitter taste transduction of nicotine, acetylcholine and ethanol.
Alkahtan, Reem M. +6 more
core +8 more sources
Implementation Science, 2019 Background Clinical decision support systems (CDSSs) may promote practitioner adherence to evidence-based guidelines. This study examined if the addition of a CDSS influenced practitioner delivery of a brief intervention with treatment-seeking smokers ...
Nadia Minian +9 more
doaj +1 more source