Results 41 to 50 of about 465,225 (381)

Acute effects of nicotine on visual search tasks in young adult smokers [PDF]

, 2005
Rationale Nicotine is known to improve performance on tests involving sustained attention and recent research suggests that nicotine may also improve performance on tests involving the strategic allocation of attention and working memory.
A Miyake, A Olincy, AD Revell, AL Larrison, AM Treisman, B Baldinger, C Araujo, C Parkin, C Stough, CM Butter, DM Warburton, DM Warburton, DY Kimberg, EA Witte, ED Levin, G Mancuso, GF Woodman, HK White, J Foulds, J Houezec Le, J Powell, JC Thompson, Jennifer M. Rusted, JM Wolfe, K Wesnes, K Wesnes, KO Fagerström, L Depatie, M Ernst, M Trimmel, MT Avila, Nicola Rycroft, P Rabbit, RJ Roberts, RJ West, Samuel B. Hutton, SB Hutton, SB Hutton, T Bates, T Edginton, TP George, V Della Casa, V Della Casa, V Kumari, WS Griesar, WS Pritchard   +45 more
core   +2 more sources

Neural signatures of cognitive flexibility and reward sensitivity following nicotinic receptor stimulation in dependent smokers : a randomized trial [PDF]

, 2017
IMPORTANCE Withdrawal from nicotine is an important contributor to smoking relapse. Understanding how reward-based decision making is affected by abstinence and by pharmacotherapies such as nicotine replacement therapy and varenicline tartrate may aid ...
Aronson, Sarah E., Lesage, Elise, Ross, Thomas J., Salmeron, Betty Jo, Stein, Elliot A., Sutherland, Matthew T.   +5 more
core   +2 more sources

Personalized dosing of nicotine replacement therapy versus standard dosing for the treatment of individuals with tobacco dependence: study protocol for a randomized placebo-controlled trial

Trials, 2020
Background Medications for smoking cessation are currently only effective in helping a minority of smokers quit. Drug development is slow and expensive; as such, there is much interest in optimizing the effectiveness of existing treatments and ...
Laurie Zawertailo, Christian S. Hendershot, Rachel F. Tyndale, Bernard Le Foll, Andriy V. Samokhvalov, Kevin E. Thorpe, Andrew Pipe, Robert D. Reid, Peter Selby   +8 more
doaj   +1 more source

Identification of nicotine-seeking and avoiding larval zebrafish using a new three-choice behavioral assay

Frontiers in Molecular Neuroscience, 2023
IntroductionNicotine dependence is one of the main causes of preventable diseases in the United States. Nicotine-seeking and avoidance behavioral assays in larval zebrafish could be used for identifying potential new pharmacotherapeutics in an early ...
Henning Schneider, Anna Pearson, Drew Harris, Sabrina Krause, Andrew Tucker, Kaitlyn Gardner, Kuzivakwashe Chinyanya   +6 more
doaj   +1 more source

Harm Minimization and Tobacco Control: Reframing Societal Views of Nicotine Use to Rapidly Save Lives.

Annual Review of Public Health, 2018
Inhalation of the toxic smoke produced by combusting tobacco products, primarily cigarettes, is the overwhelming cause of tobacco-related disease and death in the United States and globally. A diverse class of alternative nicotine delivery systems (ANDS)
D. Abrams, Allison M. Glasser, Jennifer L. Pearson, Andrea C. Villanti, Lauren K. Collins, R. Niaura   +5 more
semanticscholar   +1 more source

Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine [PDF]

, 2013
Nicotine exerts its reinforcing action by stimulating nicotinic acetylcholine receptors (nAChRs) and boosting dopamine (DA) output from the ventral tegmental area (VTA).
A Taly, AA Grace, AJ Yu, AO Komendantov, AR Tapper, B Buisson, B Katz, Boris Gutkin, C Lüscher, C Shelley, CP Fenster, DB Carr, E Lichtenstein, E Sher, EJ Nestler, F Marti, FE Pontieri, G Di Chiara, G Di Chiara, G Di Chiara, GL Forster, HD Mansvelder, HD Mansvelder, HR Wilson, IW Jones, J Cornwall, J Grenhoff, JA Dani, Ja Dani, JB Eaton, JE Henningfield, JE Rose, JN Reynolds, JP Changeux, JP Changeux, JP Changeux, JR Clements, JR Wooltorton, K Chergui, Karl J. Friston, KG Paradiso, LE Chavez-Noriega, M Gao, M Garzón, M Graupner, M Mameli-Engvall, M Wu, MG Lacey, Michael Graupner, MJ Christie, MR Picciotto, MR Picciotto, N Champtiaux, P Dayan, PW Kalivas, R Exley, R Giniatullin, R Klink, R Nashmi, Reinoud Maex, RL Papke, S Erhardt, S Ikemoto, S Tolu, SA Oakman, SC Steffensen, SR Grady, SR Sesack, SW Johnson, SW Johnson, TC Jhou, V David, V Gerzanich, V Gerzanich, VI Pidoplichko, WA Corrigall, X Peng, ZM Fagen, ZY Tong   +78 more
core   +5 more sources

Differences in nicotine metabolism of two Nicotiana attenuata herbivores render them differentially susceptible to a common native predator. [PDF]

PLoS ONE, 2014
Nicotiana attenuata is attacked by larvae of both specialist (Manduca sexta) and generalist (Spodoptera exigua) lepidopteran herbivores in its native habitat. Nicotine is one of N. attenuata's important defenses. M.
Pavan Kumar, Preeti Rathi, Matthias Schöttner, Ian T Baldwin, Sagar Pandit   +4 more
doaj   +1 more source

Nicotine and nicotinic receptors in the circadian system

Psychoneuroendocrinology, 1998
Considerable data support a role for cholinergic influences on the circadian system. The extent to which these influences are mediated by nicotinic acetylcholine receptors (nAChRs) has been controversial, as have the specific actions of nicotine and acetylcholine in the suprachiasmatic nucleus (SCN) of the hypothalamus.
Thomas S. Kilduff, Bruce F. O'Hara, Dale M. Edgar, Joseph D. Miller, Steven W. Wiler, H. Craig Heller, Vinh H. Cao   +6 more
openaire   +3 more sources

Comparative evaluation of the efficacy of nicotine chewing gum and nicotine patches as nicotine replacement therapy using salivary cotinine levels as a biochemical validation measure

Indian Journal of Psychiatry, 2023
Background: Nicotine replacement therapy (NRT) and habit cessation counseling are considered the mainstay treatment for high nicotine dependence smokers. However, adherence to NRT is very poor.
T Sivasankari, Avudaiappan Sankaran, Senthil Murugappan, Veni Subramanyam, Balanehru Subramanian, RC Jagat Reddy, S Vandana   +6 more
doaj   +1 more source

Does it come from tobacco? Young adults' interpretations of the term "tobacco-free nicotine" in a cross-sectional national survey sample.

PLoS ONE, 2022
Background"Tobacco-free" nicotine (TFN) e-cigarettes and nicotine pouches containing synthetic nicotine are increasingly available. The term TFN may lead to reduced risk perceptions and increased use intentions relative to tobacco-derived nicotine ...
Meghan E Morean, Krysten W Bold, Danielle R Davis, Grace Kong, Suchitra Krishnan-Sarin, Deepa R Camenga   +5 more
doaj   +2 more sources