Results 71 to 80 of about 465,225 (381)

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin, Gregory Sahagian, Marc H. Feinberg, C. Andrew Stewart, Christopher M. Jewell, Metin Kurtoglu, Miloš D. Miljković, Tuan Vu, Tahseen Mozaffar, James F. Howard Jr, the MG‐001 Study Group   +10 more
wiley   +1 more source

Developmental Effects of Nicotine Exposure in Drosophila Melanogaster [PDF]

, 2017
Approximately 12%-20% of pregnant women smoke at some point during pregnancy, and 10% of pregnant women are reported to have smoked during the last 3 months of pregnancy.
Wong, Lisa Janet
core   +1 more source

Identifying determinants of varenicline adherence using the Theoretical Domains framework: a rapid review

BMC Public Health
Background Adhering to varenicline has been shown to significantly improve the chances of successfully quitting smoking, with studies indicating a twofold increase in 6-month quit rates.
Nadia Minian, Melissa Wong, Sowsan Hafuth, Terri Rodak, Alma Rahimi, Dea Gjomema, Jonathan Rose, Laurie Zawertailo, Matt Ratto, Peter Selby   +9 more
doaj   +1 more source

Identification and Quantitation of Nicotine Polacrilex in Nicotine Pouches and Other Oral Nicotine Delivery Products

Contributions to Tobacco and Nicotine Research, 2023
Nicotine polacrilex (CAS-No. 96055-45-7) can be used as the source of nicotine in nicotine pouches and other oral nicotine delivery products such as lozenges, tablets, and gums.
Moldoveanu Serban C.
doaj   +1 more source

Temporal trends in and associations with nonsteroidal anti‐inflammatory drug prescription in adult and pediatric patients with inflammatory bowel disease

Arthritis Care &Research, Accepted Article.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against NSAID use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal trends in prescription NSAID and ...
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

The antisaccade task as an index of sustained goal activation in working memory: modulation by nicotine [PDF]

, 2006
The antisaccade task provides a laboratory analogue of situations in which execution of the correct behavioural response requires the suppression of a more prepotent or habitual response.
A Nordberg, AL Larrison, AL Larrison-Faucher, B Fischer, B Reuter, C Massen, C Pierrot-Deseilligny, C Vidal, CM Martin-Ruiz, CS Myers, D Paterson, DM Warburton, DP Munoz, DV Poltavski, E Stuyven, EA Witte, ED Levin, ED Levin, ED Levin, G Mancuso, HM Arnold, J Foulds, J Leon de, J Powell, Jennifer M. Rusted, JG Harris, JH Bettany, JJ Buccafusco, JJ Buccafusco, JM Findlay, JP Mitchell, KA Perkins, KO Fagerström, L Depatie, M Ernst, M Reuben, ME Calkins, N Rycroft, N Unsworth, Nicola Rycroft, PBS Clarke, PE Hallett, R Dar, R Godijn, RJ Leigh, RJ Roberts, RJ West, RM Eenshuistra, S Leonard, S Nieuwenhuis, SA Khan, Samuel B. Hutton, SB Hutton, SB Hutton, SB Hutton, T Bates, T Edginton, U Ettinger, U Ettinger, V Casa Della, V Kumari, V Kumari, WA Corrigall, WS Griesar, YBWEM Roos   +64 more
core   +1 more source

At‐Home Early Diagnosis of Mastitis: Calibration‐Free Analysis of Sodium to Potassium Ratio in Breast Milk

Advanced Functional Materials, EarlyView.
MAMAWEL is introduced as the first calibration‐free potentiometric sensor for at‐home mastitis diagnosis. By measuring the sodium‐to‐potassium ratio in breast milk, the device reliably differentiates between healthy and mastitis‐affected samples with less than 10% error.
Ali Soleimani, Farbod Amirghasemi, Melissa Banks, Abdulrahman Al‐Shami, Sina Khazaee Nejad, Abdalrhman Sheer, Clare Dominique Sanchez, Haozheng Ma, Daniel Vargas Ramos, Maral P.S. Mousavi   +9 more
wiley   +1 more source

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Benigno, Arcangelo, Di Giovanni, Giuseppe, Muscat, Richard, Pierucci, Massimo, Pitruzzella, Alessandro, Valentino, Mario, Zammit, Christian   +6 more
core   +1 more source

Measurement of environmental tobacco smoke exposure among adults with asthma. [PDF]

, 2001
Because the morbidity and mortality from adult asthma have been increasing, the identification of modifiable environmental exposures that exacerbate asthma has become a priority. Limited evidence suggests that exposure to environmental tobacco smoke (ETS)
Blanc, PD, Eisner, MD, Hammond, SK, Katz, PP, Yelin, EH   +4 more
core   +2 more sources

Pharmacokinetic and pharmacodynamic studies of nicotine in rat brain: a simultaneous investigation of nicotine metabolites and the release of neurotransmitters in vivo

Frontiers in Chemistry, 2023
Introduction: The body’s ability to metabolize nicotine and the disposition of nicotine in the brain are important determinants of its exposure. Limited knowledge about the near real-time changes of neurochemicals during the brain nicotine metabolic ...
Lulu Guo, Lulu Guo, Lulu Guo, Jian Mao, Jian Mao, Qidong Zhang, Wu Fan, Dingzhong Wang, Zhonghao Li, Jiaqiang Huang, Jianping Xie, Jianping Xie, Jianping Xie   +12 more
doaj   +1 more source