Results 21 to 30 of about 38,909 (257)

Nicotine Addiction [PDF]

open access: yesNew England Journal of Medicine, 1999
Nicotine maintains tobacco addiction. Nicotine acts on nicotinic cholinergic receptors, which demonstrate diversity in subunit structure, function, and distribution in the nervous system, mediating the multiple actions of nicotine described in tobacco users.
openaire   +3 more sources

Cocreation of a conversational agent to help patients adhere to their varenicline treatment: A study protocol

open access: yesDigital Health, 2023
Objective Varenicline is the most efficacious approved smoking cessation medication, making it one of the most cost-effective clinical interventions for reducing tobacco-related morbidity and mortality. Adhering to varenicline is strongly associated with
Nadia Minian   +7 more
doaj   +1 more source

The effect of a clinical decision support system on prompting an intervention for risky alcohol use in a primary care smoking cessation program: a cluster randomized trial

open access: yesImplementation Science, 2019
Background Clinical decision support systems (CDSSs) may promote practitioner adherence to evidence-based guidelines. This study examined if the addition of a CDSS influenced practitioner delivery of a brief intervention with treatment-seeking smokers ...
Nadia Minian   +9 more
doaj   +1 more source

Predisposing and protective factors influencing suicide ideation, attempt, and death in patients accessing substance use treatment: a systematic review and meta-analysis protocol

open access: yesSystematic Reviews, 2019
Background The lifetime risk of suicide in patients with substance use disorder is five to ten times the risk in the general population. Critically, up to 19% of patients continue to think about and attempt suicide even after accessing treatment ...
S. Espinet   +10 more
doaj   +1 more source

Genetic influences impacting nicotine use and abuse during adolescence: Insights from human and rodent studies

open access: yesBrain Research Bulletin, 2022
Nicotine use continues to be a major public health concern, with an alarming recent rise in electronic cigarette consumption. Heritability estimates of nicotine use and abuse range from 40% to 80%, providing strong evidence that genetic factors impact ...
Lisa R. Goldberg, Thomas J. Gould
doaj   +1 more source

LEVELS OF NICOTINE ADDICTION IN CONSUMERS OF THE LATEST TOBACCO PRODUCTS

open access: yesActa Medica Leopoliensia, 2023
Aim. Determining the level of nicotine addiction in consumers of the latest tobacco products. Materials and Methods. We have surveyed 817 young people (from 18 to 45 years of age) living in Lviv region. Among them, two focus groups were distinguished:
Svitlana Kozii-Bredelieva   +1 more
doaj   +1 more source

Neurophysiology of Nicotine Addiction [PDF]

open access: yesJournal of Addiction Research & Therapy, 2012
Tobacco use is a major health problem, and nicotine is the main addictive component. Nicotine binds to nicotinic acetylcholine receptors (nAChR) to produce its initial effects. The nAChRs subtypes are composed of five subunits that can form in numerous combinations with varied functional and pharmacological characteristics.
John A, Dani   +3 more
openaire   +2 more sources

Personalized dosing of nicotine replacement therapy versus standard dosing for the treatment of individuals with tobacco dependence: study protocol for a randomized placebo-controlled trial

open access: yesTrials, 2020
Background Medications for smoking cessation are currently only effective in helping a minority of smokers quit. Drug development is slow and expensive; as such, there is much interest in optimizing the effectiveness of existing treatments and ...
Laurie Zawertailo   +8 more
doaj   +1 more source

SUATU KAJIAN MOLEKULER KETERGANTUNGAN NIKOTIN

open access: yesJurnal Farmasi Sains dan Komunitas, 2016
: Nicotine, a simple chemical substance from tobacco, stimulates addiction by neuroadaptation inducing rewards system in human brain. Molecular mechanism of nicotine addiction in rewards system are mediated by nicotinic acetylcholine receptor (nAChR) and 
Agustina Setiawati
doaj   +1 more source

Targeting Nicotine Addiction

open access: yesClinical Journal of Oncology Nursing, 2018
Smoking cessation remains a high priority in oncology nursing practice. That priority gained additional visibility in 2014 when the Oncology Nursing Society (ONS) endorsed the tobacco position statement of the International Society of Nurses in Cancer Care, emphasizing the potential for nurses to reduce adult and youth tobacco use.
openaire   +3 more sources

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