Results 71 to 80 of about 47,631 (255)

Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making

Epilepsia, EarlyView.
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe, František Bartoš, Eric‐Jan Wagenmakers, Kees P. J. Braun, Floor E. Jansen, Willem M. Otte   +5 more
wiley   +1 more source

Nicotine Dependence among Rural-Urban Migrants in China

BMC Public Health, 2011
Background The complex mechanism of nicotine dependency makes it challenging to evaluate dependence or progress towards dependence. The aim of this study was to estimate nicotine dependence levels and identify determinants of dependence among Chinese ...
Li Yuyan, Karalic Sejla, Xing Rui, Rockett Ian RH, Yang Tingzhong, Wu Junqing, Zhang Yufeng   +6 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Epidemiology, radiology, and genetics of nicotine dependence in COPD

Respiratory Research, 2011
Background Cigarette smoking is the principal environmental risk factor for developing COPD, and nicotine dependence strongly influences smoking behavior.
Hokanson John E, Washko George R, Hersh Craig P, Kim Deog Kyeom, Lynch David A, Newell John D, Murphy James R, Crapo James D, Silverman Edwin K   +8 more
doaj   +1 more source

Development of an Innovative and Functional Yerba Mate—Lychee Beverage: Sensory and Physicochemical Characteristics

Food Safety and Health, EarlyView.
A mixed beverage of yerba mate and lychee was developed and optimized. The 70:30 lychee‐to‐mate formulation provided the best balance of antioxidant activity and consumer acceptance, highlighting its potential as a functional beverage. ABSTRACT The development of functional beverages that combine bioactive compounds with sensory appeal is of growing ...
Marcela Moreira Terhaag, Leonel Vinícius Constantino, Lycio Shinji Watanabe, Tiago Bervelieri Madeira, Suzana Lucy Nixdorf, Marta de Toledo Benassi, Fábio Yamashita, Sandra Helena Prudencio   +7 more
wiley   +1 more source

Augmenting varenicline treatment with transcranial direct current stimulation (tDCS) increases smoking abstinence rates at end of treatment

Brain Stimulation, 2023
Helena Zhang, Tarek K. Rajji, Peter Selby, Osnat Melamed, Sophia Attwells, Laurie Zawertailo   +5 more
doaj   +1 more source

Critical Synthesis Package: Fagerstrom Test for Nicotine Dependence

MedEdPORTAL, 2014
This Critical Synthesis Package contains: (1) a Critical Analysis of the psychometric properties and applications to health sciences education for the Fagerstrom Test for Nicotine Dependence (FTND), and (2) a copy of the FTND instrument and scoring key ...
Sherrie Wilcox, Sarah Redmond
doaj   +1 more source

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

Gut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei, Xin‐Wei Sun, Hao‐Jie Huang, Yu‐Zhi Zhao, Shuang‐Jiang Liu, Chang Liu   +5 more
wiley   +1 more source

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili, Paolo Bossi, Luca Lalli, Lisa Francesca Linda Licitra, Marta Maddalo, Almalina Bacigalupo, Liliana Belgioia, Jon Cacicedo, Nadia Facchinetti, Almudena Garcia Castano, Marc Oliva, Pierluigi Bonomo, Giuseppe Sanguineti, Pierfrancesco Franco, Athanassios Argiris, Amanda Psyrri, Ester Orlandi   +16 more
wiley   +1 more source

Experimental Factors and Techniques for Pool Boiling Heat Transfer Enhancement: A Critical Review

Heat Transfer, EarlyView.
ABSTRACT This review presents a comprehensive assessment of active strategies for enhancing pool boiling heat transfer, with a focus on techniques that do not rely solely on the boiling surface modification. It examines a broad range of methodologies including fluid additives, external fields, mechanical interventions, and thermal‐geometric tuning that
José E. Pereira, R. R. Souza, A. S. Moita   +2 more
wiley   +1 more source