Results 41 to 50 of about 107,703 (261)

Distribution of Nicotinic Receptors in the Human Brain: Quantitative Autoradiography Using 3H-Nicotine

open access: yes, 1988
Several studies showed clearly that the mammalian central nervous system possess nicotinic receptors. Recently, using membrane receptor binding studies the regional distribution of 3H-nicotine and/or H-acetylcholine binding sites in the human brain has ...
Abdu Adem   +9 more
core   +1 more source

Oxidation of cholesterol-26-C14 by rat liver mitochondria: effect of nicotinic acid*

open access: yesJournal of Lipid Research, 1960
The effect of nicotinic acid upon the oxidation of the terminal carbon atoms of cholesterol-26-C14 by rat liver mitochondrial preparations has been studied.
David Kritchevsky   +2 more
doaj   +1 more source

Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors [PDF]

open access: yes, 2013
Venoms from cone snails (Conidae) have been extensively studied during the last decades, but those from other members of the suborder Toxoglossa, such as of Terebridae and Turridae superfamilies attracted less interest so far. Here, we report the effects
Wunder, C.   +26 more
core   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among US Veterans

open access: yesArthritis Care &Research, EarlyView.
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler   +20 more
wiley   +1 more source

Lack of nicotinic acid effect on cholesterol metabolism of the rat*

open access: yesJournal of Lipid Research, 1960
The effect of the addition of 1 per cent nicotinic acid to the diet of the rat on serum, liver, and carcass cholesterol, and on the incorporation of acetate-1-C14 into cholesterol by the intact animal were studied.
Charles H. Duncan, Maurice M. Best
doaj   +1 more source

Structurally similar allosteric modulators of α7 nicotinic acetylcholine receptors exhibit five distinct pharmacological effects. [PDF]

open access: yes, 2015
Activation of nicotinic acetylcholine receptors (nAChRs) is associated with the binding of agonists such as acetylcholine to an extracellular site that is located at the interface between two adjacent receptor subunits.
Dhankher, P   +4 more
core  

Mapping the Social Network Structure and Composition of Black Individuals With Rheumatic and Musculoskeletal Conditions

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to describe the social networks of Black individuals with rheumatic and musculoskeletal conditions and understand the clustering of health‐related behaviors to inform future community‐based, peer‐led interventions. Methods We used an adapted Personal Network Survey for Clinical Research (PERSNET) to map the personal social ...
Taussia Boadi   +27 more
wiley   +1 more source

Effect of Nicotinic Acid on Sperm Characteristic and Oocyte Development after In Vitro Fertilization using Cryopreserved Boar Semen

open access: yesJournal of Animal Reproduction and Biotechnology, 2015
The objective of this study was to investigate the efficiency of nicotinic acid on sperm cryosurvival and fertilization ability in frozen-thawed boar semen. Boar semen was collected by glove-hand method and was frozen using freezing solution treated to 0,
Yu-Jin Kim   +7 more
doaj   +1 more source

Nicotinic receptors as targets for novel analgesics and anti-infl ammatory drugs

open access: yes, 2014
Nicotine and nicotinic receptors have been explored for the past three decades as a strategy for pain control. These receptors are widely expressed throughout the central and peripheral nervous system as well as immune cells.
Freitas, Kelen C.C.   +3 more
core   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

open access: yesAdvanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li   +9 more
wiley   +1 more source

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