Results 21 to 30 of about 107,703 (261)

Paying attention to smell: Cholinergic signaling in the olfactory bulb.

Frontiers in Synaptic Neuroscience, 2014
The tractable, layered architecture of the olfactory bulb (OB), and its function as a relay between odor input and higher cortical processing, makes it an attractive model to study how sensory information is processed at a synaptic and circuit level. The
Rinaldo David D'Souza, Sukumar eVijayaraghavan   +1 more
doaj   +1 more source

Single-Molecule Studies of Ion Channels Expressing Unnatural Amino Acids [PDF]

, 2011
The nicotinic acetylcholine receptors are pentameric ligand-gated ion channels that mediate fast synaptic transmission in the brain and peripheral nervous system.
Shanata, Jai Anand Pattur
core   +1 more source

Acetylcholine release and inhibitory interneuron activity in hippocampal CA1

Frontiers in Synaptic Neuroscience, 2014
Acetylcholine release in the central nervous system (CNS) has an important role in attention, recall and memory formation. One region influenced by acetylcholine is the hippocampus, which receives inputs from the medial septum and diagonal band of Broca ...
A. Rory McQuiston
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AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity [PDF]

, 2007
Neuronal nAChRs are a diverse family of pentameric ion channels with wide distribution throughout cells of the nervous and immune systems. However, the role of specific subtypes in normal and pathological states remains poorly understood due to the lack ...
Sixma, Titia K., Alewood, Paul F., Buettner, Regina, van Elk, R, Smit, A.B., Sixma, T., Dutertre, S., Nicke, A, van Elk, R., Smit, A., Nicke, Annette, Alewood, P. F., Sixma, T.K., Kendel, Y., Smit, AB, Lewis, R. J., Hopping, G., Kendel, Y, van Elk, René, Büttner, Regina, Elk, René van, Ulens, C, Ulens, Chris, Buttner, R, Kendel, Yvonne, Sixma, TK, Fish, Alexander, Lewis, R.J., Schroeder, Christina, Lewis, Richard,, Smit, August,, Buttner, R., Elk, R. van, Alewood, P.F., Lewis, Richard J., Fish, A, Sixma, Titia,, Schroeder, C., Alewood, Paul,, Fish, A., Alewood, P., Dutertre, Sébastien, Smit, August B., Ulens, C., Hopping, Gene, Nicke, A., Lewis, R.   +46 more
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Improved Cholinergic Transmission is Detrimental to Behavioural Plasticity in Honeybees (Apis mellifera)

Biology, 2012
Unravelling the role of neuromessenger processes in learning and memory has long interested researchers. We investigated the effects of an acetylcholinesterase blocker, Methyl Parathion (MeP), on honeybee learning.
Shao-Wu Zhang, Hong Zhu, David Guez
doaj   +1 more source

Learning and nicotine interact to increase CREB phosphorylation at the jnk1 promoter in the hippocampus [PDF]

, 2012
Nicotine is known to enhance long-term hippocampus dependent learning and memory in both rodents and humans via its activity at nicotinic acetylcholinergic receptors (nAChRs).
Rachel L Poole, Gould, Thomas J., Michael D Adoff, Gould Thomas J., Kenney, Justin W., Thomas J Gould, Poole Rachel L., Poole, Rachel L., Logue, Sheree F., Kenney Justin W., Justin W Kenney, Sheree F Logue, Logue Sheree F., Adoff, Michael D., Adoff Michael D.   +14 more
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Congenital myasthenic syndromes: Clinical and molecular report on 7 Sicilian patients

Journal of Pediatric Neurosciences, 2013
Background: Congenital myasthenic syndromes (CMS) are a heterogeneous group of diseases involving neuromuscular transmission. The classification of these syndromes is based on the localization of the defect (pre-synaptic, post-synaptic, and neuromuscular
Piero Pavone, Agata Polizzi, Maria Roberta Longo, Katia Romano, Michele Vecchio, Andrea D Praticò, Raffaele Falsaperla   +6 more
doaj   +1 more source

Heterogenous Cholinergic Nicotinic Receptors in the CNS

, 1988
Multiple nicotinic binding sites are found in mammalian brain. Several nicotinic agonists and antagonists have been used to characterize the nicotinic binding sites.
Nilsson, L, Abdu Adem, Luciana Romanelli, Nordberg, A, Lena Nilsson, Adem, A, Xiao Zhang, Zhang, X, Agneta Nordberg, Romanelli, L   +9 more
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Nicotinic acid: a lipid-lowering agent with unrealized potential

The Egyptian Journal of Internal Medicine, 2014
Nicotinic acid is a well-known treatment for dyslipidemia in adults. This review article explored not only the role of nicotinic acid in dyslipidemia but also its role in hypertension and as a cardioprotective agent.
Samar H. Aboulsoud
doaj   +1 more source

Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines. [PDF]

PLoS ONE, 2015
Standard treatment of poisoning by organophosphorus anticholinesterases uses atropine to reduce the muscarinic effects of acetylcholine accumulation and oximes to reactivate acetylcholinesterase (the effectiveness of which depends on the specific ...
Avi Ring, Bjorn Oddvar Strom, Simon R Turner, Christopher M Timperley, Michael Bird, A Christopher Green, John E Chad, Franz Worek, John E H Tattersall   +8 more
doaj   +1 more source