Results 31 to 40 of about 75,040 (266)

Lack of nicotinic acid effect on cholesterol metabolism of the rat*

Journal of Lipid Research, 1960
The effect of the addition of 1 per cent nicotinic acid to the diet of the rat on serum, liver, and carcass cholesterol, and on the incorporation of acetate-1-C14 into cholesterol by the intact animal were studied.
Charles H. Duncan, Maurice M. Best
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

The Anti-Aggregative Peptide KLVFF Mimics Aβ1-40 in the Modulation of Nicotinic Receptors: Implications for Peptide-Based Therapy

Biomedicines, 2022
In recent years, the inhibition of beta-amyloid (Aβ) aggregation has emerged as a potential strategy for Alzheimer’s disease. KLVFF, a small peptide corresponding to the aminoacidic sequence 16-20 of Aβ, reduces Aβ fibrillation dose dependently ...
Hanna Trebesova, Guendalina Olivero, Mario Marchi, Massimo Grilli   +3 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Effect of Nicotinic Acid on Sperm Characteristic and Oocyte Development after In Vitro Fertilization using Cryopreserved Boar Semen

Journal of Animal Reproduction and Biotechnology, 2015
The objective of this study was to investigate the efficiency of nicotinic acid on sperm cryosurvival and fertilization ability in frozen-thawed boar semen. Boar semen was collected by glove-hand method and was frozen using freezing solution treated to 0,
Yu-Jin Kim, Sang-Hee Lee, Yeon-Ju Lee, Hae-In Oh, Hee-Tae Cheong, Boo-Keun Yang, Seunghyung Lee, Choon-Keun Park   +7 more
doaj   +1 more source

Nicotine and neuronal nicotinic acetylcholine receptors: unraveling the mechanisms of nicotine addiction

Frontiers in Neuroscience
Nicotine, recognized as the principal addictive component in tobacco, is mechanistically linked to its interaction with neuronal nicotinic acetylcholine receptors (nAChRs). nAChRs are ligand-gated ion channels composed of five transmembrane subunits, with the α4β2 receptor subtype being the most common in the brain, playing a crucial role in the ...
Jian, Jiang, Xia, Li, An-Fu, Hu, Guo-Jun, Zhou, Yi-Han, Gao, Chengyun, Xu, Xi-Mei, Wu, Hong-Juan, Wang   +7 more
openaire   +2 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Developmental sex differences in nicotinic currents of prefrontal layer VI neurons in mice and rats.

PLoS ONE, 2010
BackgroundThere is a large sex difference in the prevalence of attention deficit disorder; yet, relatively little is known about sex differences in the development of prefrontal attention circuitry.
Nyresa C Alves, Craig D C Bailey, Raad Nashmi, Evelyn K Lambe   +3 more
doaj   +1 more source

Electrolyte‐Induced Cu+ Preservation Results in a Selectivity Switch of Electrocatalytic CO2 Reduction at a Copper‐Organic Framework as Electrocatalyst

Advanced Functional Materials, EarlyView.
The active role of KCl as a neutral electrolyte enables switching the selectivity on a Cu organic framework from C1 to C2+ products during electrocatalytic CO2 reduction. ABSTRACT We introduce a copper‐nicotinate (Cu‐NA) framework as a halogenide‐stabilized Cu+/Cu0 pre‐catalyst for electrocatalytic CO2 reduction with high C2+ selectivity in a “neutral”
Anirudha Shekhawat, Muhammad Adib Abdillah Mahbub, Lejing Li, Bashir Eid, Ridha Zerdoumi, Sabine Seisel, Carla Santana Santos, Nini Zhang, Thomas Quast, Xin Wang, Wolfgang Schuhmann, Debanjan Das   +11 more
wiley   +1 more source

Solution thermodynamics of aqueous nicotinic acid solutions in presence of tetrabutylammonium hydrogen sulphate [PDF]

Journal of the Serbian Chemical Society, 2013
In this study we investigated the effects of tetrabutylammonium hydrogen sulphate (Bu4NHSO4) on the solute-solute and solute-solvent interactions in the aqueous solutions of nicotinic acid in terms of apparent molar volumes (φV), standard partial ...
Sarkar Abhijit, Sinha Biswajit
doaj   +1 more source