Results 131 to 140 of about 76,692 (268)

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker   +2 more
wiley   +1 more source

Chemoreflex function in pulmonary diseases – A review

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Chemoreflex activation in respiratory diseases and COVID‐19 populations. Abstract The chemoreflex is a vital protective reflex that is crucial in restoring normal blood gas and pH levels. The carotid bodies are peripheral chemoreceptors activated by hypoxia (primarily), hypercapnia, acidaemia, temperature, lactate and potassium ...
Kajal Kamra   +4 more
wiley   +1 more source

The mysterious middlemen making your vision pop: understanding the function of amacrine cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This review aims to illustrate the diversity and function of amacrine cells in the retina. The diversity of amacrine cell subtypes is depicted based on morphology, stratification and neurotransmitter expression, along with their synaptic connectivity with bipolar and ganglion cells, emphasizing inhibitory and modulatory roles ...
Victor Calbiague‐Garcia   +3 more
wiley   +1 more source

Development and Validation of a Rapid LC–MS/MS Method for Plasma Analysis of Ketamine, Norketamine, Dehydronorketamine, and Hydroxynorketamine

open access: yesBiomedical Chromatography, Volume 39, Issue 9, September 2025.
ABSTRACT Ketamine, a well‐established dissociative anesthetic, has recently gained significant attention for its rapid‐acting antidepressant effects, particularly in treatment‐resistant depression. In this study, we developed and validated a state‐of‐the‐art liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the bioanalysis of ...
Jan Thomann   +5 more
wiley   +1 more source

Differentiated Presynaptic Input to OLMɑ2 Cells Along the Hippocampal Dorsoventral Axis: Implications for Hippocampal Microcircuit Function

open access: yesHippocampus, Volume 35, Issue 5, September 2025.
ABSTRACT The dorsal and ventral hippocampus have distinct processing properties, but it remains unclear if interneuron subtypes differ in connectivity along the dorsoventral axis. Oriens lacunosum‐moleculare (OLM) interneurons, identified by the Chrna2 gene, are known to regulate memory processes differently along this axis. OLMɑ2 cells bidirectionally
Angelica Thulin   +3 more
wiley   +1 more source

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