Impulsive Behavior and Nicotinic Acetylcholine Receptors
Higher impulsivity is thought to be a risk factor for drug addiction, criminal involvement, and suicide. Excessive levels of impulsivity are often observed in several psychiatric disorders including attention-deficit/hyperactivity disorder and ...
Yu Ohmura+2 more
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Nicotinic acetylcholine receptors [PDF]
This themed section of the British Journal of Pharmacology is the product of a conference that focussed on nicotinic ACh receptors (nAChRs) that was held on the Greek island of Crete from 7 to 11 May 2017. ‘Nicotinic acetylcholine receptors 2017’ was the
S. Wonnacott+3 more
semanticscholar +8 more sources
Alzheimer’s Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts [PDF]
Biological membranes show lateral and transverse asymmetric lipid distribution. Cholesterol (Chol) localizes in both hemilayers, but in the external one it is mostly condensed in lipid-ordered microdomains (raft domains), together with saturated ...
Antollini, Silvia Susana+1 more
core +2 more sources
Phospholipases A2 represent the most abundant family of snake venom proteins. They manifest an array of biological activities, which is constantly expanding. We have recently shown that a protein bitanarin, isolated from the venom of the puff adder Bitis
Catherine A Vulfius+9 more
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Alcohol and nicotinic acetylcholine receptors [PDF]
Background The frequent co-abuse of alcohol and tobacco may suggest that they share some common neurological mechanisms. For example, nicotine acts on Nicotinic acetylcholine receptors (nAChRs) in the brain to release dopamine to sustain addiction. Might
Jinsong Tang, Yanhui Liao
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Conotoxins Targeting Nicotinic Acetylcholine Receptors: An Overview
Marine snails of the genus Conus are a large family of predatory gastropods with an unparalleled molecular diversity of pharmacologically active compounds in their venom.
Eline K. M. Lebbe+3 more
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Nicotinic acetylcholine receptors mediate lung cancer growth
Ion channels modulate ion flux across cell membranes, activate signal transduction pathways, and influence cellular transport – vital biological functions that are inexorably linked to cellular processes that go awry during carcinogenesis.
Ma. Reina eImprogo+3 more
doaj +2 more sources
Erythrina mulungu alkaloids are potent inhibitors of neuronal nicotinic receptor currents in mammalian cells. [PDF]
Crude extracts and three isolated alkaloids from Erythrina mulungu plants have shown anxiolytic effects in different animal models. We investigated whether these alkaloids could affect nicotinic acetylcholine receptors and if they are selective for ...
Pedro Setti-Perdigão+5 more
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Neuregulin upregulates microglial α7 nicotinic acetylcholine receptor expression in immortalized cell lines: implications for regulating neuroinflammation. [PDF]
Neuregulin, previously known as ARIA, is a signaling protein involved in cell survival, synaptic plasticity, cell communication and differentiation. Neuregulin has also been described as a potent inducer of acetylcholine receptor transcription in muscle ...
Malwina Mencel+2 more
doaj +1 more source
NICOTINIC RECEPTORS IN NEUROPSYCHIATRIC PATHOLOGIES OF ADULTHOOD AND DEVELOPMENTAL AGE. [PDF]
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels present in many regions of the central nervous system (CNS) and the peripheral nervous system.
Elettra Unti
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