Results 111 to 120 of about 43,248 (261)

Insights into the Structural Determinants Required for High-Affinity Binding of Chiral Cyclopropane-Containing Ligands to α4β2-Nicotinic Acetylcholine Receptors: An Integrated Approach to Behaviorally Active Nicotinic Ligands

, 2012
Han-Kun Zhang, J. Brek Eaton, Li-Fang Yu, Mieke Nys, Angelica Mazzolari, René van Elk, August B. Smit, Vadim Alexandrov, Taleen Hanania, Emily Sabath, Allison Fedolak, Daniela Brunner, Ronald J. Lukas, Giulio Vistoli, Chris Ulens, Alan P. Kozikowski   +15 more
openalex   +2 more sources

Single‐nucleus RNA sequencing identifies a novel tenogenic heterologous differentiation in endometrial carcinosarcomas: implications for diagnosis and tumor classification

The Journal of Pathology, Volume 268, Issue 2, Page 227-242, February 2026.
Abstract Carcinosarcomas (CSs) are aggressive biphasic tumors characterized by epithelial and mesenchymal components, whose histogenesis and differentiation dynamics remain poorly understood. We present single‐nucleus RNA sequencing (snRNA‐seq) analysis of six CSs (five endometrial and one ovarian) and two normal endometrial samples, profiling over 96 ...
Silvia González‐Martínez, José Palacios, Irene Carretero‐Barrio, Val Fernández‐Lanza, Alfonso Cortés‐Salgado, Javier Román, Xavier Matias‐Guiu, Sonia Gatius, Javier Cortés, Belén Pérez‐Mies   +9 more
wiley   +1 more source

Comparative multi‐omics in female mice reveals tissue‐specific vulnerabilities to chronic alcohol intake

Alcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis, Muni Swamy Ganjayi, Austin M. Brown, Samantha E. Moser, Nathaniel J. Szewczyk, Brian C. Clark, Cory W. Baumann   +6 more
wiley   +1 more source

The α3 and α4 nicotinic acetylcholine receptor (nAChR) subunits in the brainstem medulla of sudden infant death syndrome (SIDS)

, 2019
Atqiya Aishah, Tina Hinton, Karen A. Waters, Rita Machaalani   +3 more
openalex   +2 more sources

Impact of Prior Intravenous Immunoglobulin and Plasmapheresis on Eculizumab or Ravulizumab Treatment for Generalized Myasthenia Gravis: An Analysis of the MG SPOTLIGHT Registry

Clinical and Experimental Neuroimmunology, Volume 17, Issue 1, February 2026.
ABSTRACT Objective The complement component 5 inhibitor therapies (C5ITs) eculizumab and ravulizumab are approved for the treatment of generalized myasthenia gravis (gMG). We evaluated the real‐world effectiveness and safety of eculizumab and ravulizumab in patients with gMG with or without prior intravenous immunoglobulin (IVIg) or plasma exchange ...
Akiyuki Uzawa, Ema Rodrigues, Hiroyuki Murai   +2 more
wiley   +1 more source

Structure-Function Studies of the α4β2 Nicotinic Acetylcholine Receptor in a Lipidic Environment [PDF]

, 2020
Guipeun Kang
openalex   +1 more source

Dual impact of smoking cessation and post‐cessation weight change on psoriasis

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 2, Page 285-295, February 2026.
Although smoking cessation generally reduced the risk of psoriasis, especially psoriasis vulgaris and palmoplantar pustulosis, post‐cessation weight gain weakened this benefit, mainly for psoriasis vulgaris. Nonetheless, cessation maintained a substantial protective effect against palmoplantar pustulosis, and long‐term advantages outweighed the adverse
Seong Rae Kim, Young‐Geun Choi, Seong Jin Jo   +2 more
wiley   +1 more source

RETRACTED: Nicotinic acetylcholine receptor α7 subunit maybe a risk factor of seizure susceptibility

, 2019
Xu Chen, Ying Zhang, Ruidong Cheng, Jie Zhang, Jue-Bao Li, Feng‐Xia Liang, Liang Tian, Genying Zhu, Xiangming Ye, Xiao‐Ming Li, Peng Sun   +10 more
openalex   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Role of α5 Nicotinic Acetylcholine Receptors in Pharmacological and Behavioral Effects of Nicotine in Mice [PDF]

, 2010
Kia J. Jackson, Michael J. Marks, Robert E. Vann, Xing Chen, Thomas F. Gamage, Jonathan A. Warner, M. Imad Damaj   +6 more
openalex   +1 more source