Results 131 to 140 of about 43,248 (261)

Altered Functional Specialization and Interhemispheric Coordination in Rhegmatogenous Retinal Detachment: Associations With Gene Expression, Neurotransmitter Receptor Distribution, and SVM–SHAP Classification

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Autonomy Index (AI) and Connective Flexibility of Homotopic voxels (CFH) were derived from resting‐state fMRI data following standard preprocessing. These functional metrics were computed based on the AAL90 atlas to characterize intrinsic activity and interhemispheric coordination patterns in RRD patients.
Yu Ji, Yuan‐Yuan Wang, Xiao‐Rong Wu
wiley   +1 more source

Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors

open access: yesAnais da Academia Brasileira de Ciências, 2002
Several neurotransmitter systems have been related to developmental processes during the past decade. In this review, we discuss the evidence that the nicotinic acetylcholine receptors could have an additional function during development that may be ...
TORRÃO ANDRÉA S., BRITTO LUIZ R.G.
doaj  

A selective 7 nicotinic acetylcholine receptor agonist, PNU-282987, attenuates ILC2s activation and Alternaria induced airway inflammation [PDF]

open access: green, 2020
Fang Yuan   +8 more
openalex   +1 more source

Vanillin Modulates the Sedative Effect of Diazepam, Possibly Through GABAergic Interaction Pathways in Thiopental Sodium‐Induced Sleeping Mice

open access: yesFood Safety and Health, Volume 4, Issue 1, Page 220-232, January 2026.
Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh   +8 more
wiley   +1 more source

Effect of Targeted Probiotics on Anesthesia‐Induced Sleep Disturbances via Modulating the Gut Microbiome and Metabolites

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
The diversity and abundance of the gut microbiome in rats were significantly disrupted following post‐anesthesia sleep disturbance. Lactobacillales and Bifidobacterium yogurt supplementations increased sleep quality considerably and the abundance of beneficial bacteria, while reducing wakefulness and wake‐related metabolites in the gut.
Rui‐zhi Yang   +7 more
wiley   +1 more source

Spirocyclic Diamine Scaffolds for Medicinal Chemistry

open access: yesHelvetica Chimica Acta, Volume 109, Issue 1, January 2026.
Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel   +3 more
wiley   +1 more source

Nicotinic acetylcholine receptors

open access: yesScholarpedia, 2008
Jean-Pierre Changeux   +1 more
openaire   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

open access: yesJournal of Applied Toxicology, Volume 46, Issue 1, Page 179-197, January 2026.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U   +6 more
wiley   +1 more source

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