NICOTINIC ACETYLCHOLINE RECEPTORS SUBSERVING NOCICEPTION IN THE DOG HINDLIMB
Norio Taira+2 more
openalex +2 more sources
Abstract Tobacco thrips (Frankliniella fusca Hinds) feeding can reduce peanut (Arachis hypogaea L.) yield and vector Tomato spotted wilt orthotospovirus (family Tospoviridae, genus Orthotospovirus). Visible injury caused by tobacco thrips feeding was recorded from 2013 to 2022 at one location in North Carolina when peanut was not treated with ...
Brittany Pendleton+9 more
wiley +1 more source
This study cyclized conotoxin Vc1.1 using polyethylene glycol (PEG) linkers of different lengths and demonstrates that linker length modulates the peptide's helicity, thereby influencing its biological activity and stability. ABSTRACT α‐Conotoxin Vc1.1 is a disulfide‐rich peptide and a promising drug candidate for treating neuropathic and chronic pain.
Yuhui Zhang+4 more
wiley +1 more source
Monoclonal antibodies directed against the neurotransmitter binding site of nicotinic acetylcholine receptor [PDF]
Richard W. James+3 more
openalex +1 more source
Inhibition of nicotinic acetylcholine receptors by oligoarginine peptides and polyamine-related compounds. [PDF]
Ojomoko LO+11 more
europepmc +1 more source
Cyto‐Genotoxic Assessment of Sulfoxaflor in Allium cepa Root Cells and DNA Docking Studies
Cyto‐genotoxic Assessment of Sulfoxaflor in Allium cepa Root Cells and DNA Docking Studies. ABSTRACT Sulfoxaflor (SFX) is an insecticide that is commonly used for the control of sap‐feeding insects. Since SFX is extensively applied globally, it has been implicated in the substantial induction of environmental toxicity.
Recep Liman+7 more
wiley +1 more source
Three-dimensional structure of the nicotinic acetylcholine receptor and location of the major associated 43-kD cytoskeletal protein, determined at 22 A by low dose electron microscopy and x-ray diffraction to 12.5 A [published erratum appears in J Cell Biol 1989 Oct;109(4 Pt 1):1185] [PDF]
Alok K. Mitra
openalex +1 more source
Discovery and biological characterization of a novel mesoionic insecticide fenmezoditiaz
Acetylcholine binding protein (AChBP) from the sea slug Aplysia californica was modified using site‐directed mutagenesis to create an insect‐like binding site enabling structure‐based compound design. Fenmezoditiaz is a systemic insecticide with a broad spectrum, lack of cross‐resistance and an additional tool for integrated pest management and ...
Huazhang Huang+8 more
wiley +1 more source
Lung cancer is the leading cause of cancer death worldwide and new treatment strategies are clearly needed. The recent discovery that lung and other cancers synthesize and secrete acetylcholine (ACh) which acts as an autocrine growth factor suggests that
Therapy Pingfang Song, Eliot R. Spindel
doaj