Results 171 to 180 of about 140,109 (356)

Basic and Clinical Aspects of Non-neuronal Acetylcholine: Expression of Non-neuronal Acetylcholine in Lung Cancer Provides a New Target for Cancer

Journal of Pharmacological Sciences, 2008
Lung cancer is the leading cause of cancer death worldwide and new treatment strategies are clearly needed. The recent discovery that lung and other cancers synthesize and secrete acetylcholine (ACh) which acts as an autocrine growth factor suggests that
Therapy Pingfang Song, Eliot R. Spindel
doaj  

Sugar Addiction: Neural Mechanisms and Health Implications

Brain and Behavior, Volume 15, Issue 7, July 2025.
This review synthesizes recent advances in understanding sugar addiction with a focus on its neurobiological mechanisms, health implications, and potential therapeutic interventions. ABSTRACT Purpose Sugar addiction, characterized by excessive cravings for high‐sugar foods, poses a significant health challenge in modern society.
Di Qin, Jiayu Qi, Fuqiang Shi, Zhihua Guo, Hongwu Li   +4 more
wiley   +1 more source

Miscibility gap of octyl glucoside-phosphatidylcholine micellar solutions. Partition of the nicotinic acetylcholine receptor into the surfactant-rich phase

, 1989
Theo Schürholz, Anke Gieselmann, Eberhard Neumann   +2 more
openalex   +2 more sources

Three conductance classes of nicotinic acetylcholine receptors are expressed in developing amphibian skeletal muscle [PDF]

, 1989
JL Owens, R Kullberg
openalex   +1 more source

Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors

Journal of Neurochemistry, 2017
J. Molgó, P. Marchot, R. Aráoz, É. Benoit, B. Iorga, A. Zakarian, P. Taylor, Y. Bourne, D. Servent   +8 more
semanticscholar   +1 more source

One Bite, Two Severe Envenomations Despite Antivenom Therapy: A Case Report

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT This case report describes a 12‐year‐old child who was bitten by a cobra and developed two distinct systemic neurotoxic episodes, 19 h apart, along with severe local envenoming, despite receiving appropriate treatment with antivenom and making a full recovery.
Ravi Shukla, Puja Shrestha, Binod Khanal, Shraddha Paudyal, Bipal Regmi   +4 more
wiley   +1 more source

Acetylcholine receptor based chemogenetics engineered for neuronal inhibition and seizure control assessed in mice

Nature Communications
Epilepsy is a prevalent disorder involving neuronal network hyperexcitability, yet existing therapeutic strategies often fail to provide optimal patient outcomes. Chemogenetic approaches, where exogenous receptors are expressed in defined brain areas and
Quynh-Anh Nguyen, Peter M. Klein, Cheng Xie, Katelyn N. Benthall, Jillian Iafrati, Jesslyn Homidan, Jacob T. Bendor, Barna Dudok, Jordan S. Farrell, Tilo Gschwind, Charlotte L. Porter, Annahita Keravala, G. Steven Dodson, Ivan Soltesz   +13 more
doaj   +1 more source

Formation of the alpha-bungarotoxin binding site and assembly of the nicotinic acetylcholine receptor subunits occur in the endoplasmic reticulum.

, 1987
McHardy M. Smith, Jon Lindstrom, John P. Merlie   +2 more
openalex   +1 more source

Metabolic stability and antigenic modulation of nicotinic acetylcholine receptors on bovine adrenal chromaffin cells. [PDF]

, 1988
Linda S. Higgins, D K Berg
openalex   +1 more source

Immune Checkpoint Inhibitor‐Related Dysautonomia in Merkel Cell Carcinoma: A Case Report

Cancer Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block inhibitory pathways that cancer cells exploit to suppress T‐cell activation. Although immune‐related adverse events (irAEs) linked to ICI therapy are well documented and encompass dermatologic, endocrine, gastrointestinal, hepatic, and neurologic systems, ICI ...
Nidhi Kuchimanchi, Sai Gajula, Elizabeth M. Gaughan, Russell G. Witt   +3 more
wiley   +1 more source