Results 141 to 150 of about 5,257,547 (397)

Altered Hippocampal Transcriptomic Profile Reveals Cognitive Impairment in Young Metabolically Obese, Normal‐Weight Rats, Prevented by Perinatal Leptin Intake

Molecular Nutrition &Food Research, EarlyView.
Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
Carmen García‐Ruano, Andrea Costa, Andreu Palou, Paula Oliver   +3 more
wiley   +1 more source

Nicotinic Acid-Mediated Modulation of Metastasis-Associated Protein 1 Methylation and Inflammation in Brain Arteriovenous Malformation. [PDF]

Biomolecules, 2023
Deng X, Zhou S, Hu Z, Gong F, Zhang J, Zhou C, Lan W, Gao X, Huang Y.   +8 more
europepmc   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Nicotinic Acid Catabolism Modulates Bacterial Mycophagy in Burkholderia gladioli Strain NGJ1. [PDF]

Microbiol Spectr, 2023
Das J, Kumar R, Yadav SK, Jha G.
europepmc   +1 more source

FURTHER STUDIES ON THE METABOLISM OF TRYPTOPHAN AND NICOTINIC ACID BY THE RAT AND OTHER ANIMALS

, 1948
B.S. Schweigert, P. B. Pearson
openalex   +1 more source

Observations on the Curative Effect of Nicotinic Acid and of Liver in the Canine Black Tongue Disease¹ [PDF]

, 1938
R Nicolaysen, Per Laland
openalex   +1 more source

Expanding the Reach of Membrane Protein–Ligand Interaction Studies Through the Integration of Mass Spectrometry and Membrane Mimetics

PROTEOMICS, EarlyView.
ABSTRACT Mass spectrometry (MS) offers robust, label‐free approaches for characterizing ligand–protein interactions through two main strategies: affinity‐based and stability‐based assays. However, their application to membrane proteins (MPs)—a major class of drug targets—has been limited by challenges such as structural complexity, low native ...
Jonathon C. Lambos, Ashim Bhattacharya, Mohammed Al‐Seragi, Franck Duong van Hoa   +3 more
wiley   +1 more source

Nicotinic acid supplementation contributes to the amelioration of Alzheimer's disease in mouse models. [PDF]

Ann Transl Med, 2022
Wang Z, Zou Z, Li Q.
europepmc   +1 more source

Prospective of indigenous African wild food plants in alleviation of the severe iron deficiency anaemia in Sub‐Saharan Africa

PLANTS, PEOPLE, PLANET, EarlyView.
Iron deficiency anaemia remains a major public health challenge in Sub‐Saharan Africa, where population growth, displacement and limited resources heighten nutritional insecurity. We compiled a list of indigenous African underutilized wild food plants and examined their potential for addressing micronutrient deficiencies.
Eltayb Abdellatef, Yohannes Gedamu Gebre, Petra Bauer   +2 more
wiley   +1 more source

Blood levels of nicotinic acid negatively correlate with hearing ability in healthy older men. [PDF]

BMC Geriatr, 2023
Nakagawa-Nagahama Y, Igarashi M, Miura M, Kashiwabara K, Yaku K, Fukamizu Y, Sato T, Sakurai T, Nakagawa T, Kadowaki T, Yamauchi T.   +10 more
europepmc   +1 more source