Oral nicotinic acid as a treatment for ketosis.
Changes in blood metabolites and milk production were measured in eight cows with subclinical or clinical ketosis following treatment with daily doses of 12 g nicotinic acid fed with the concentrate mixture.
T. J. Fronk, L. Schultz
semanticscholar +1 more source
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah+9 more
wiley +1 more source
Nicotine strongly activates dendritic cell-mediated adaptive immunity - potential role for progression of atherosclerotic lesions [PDF]
Background - Antigen-presenting cells (APCs) such as monocytes and dendritic cells (DCs) stimulate T-cell proliferation and activation in the course of adaptive immunity.
Aicher, A+5 more
core +1 more source
We present an economically viable approach for synthesizing carbon nanomaterials derived from discarded cigarette filters, an abundant environmental pollutant. The resulting material exhibits desirable characteristics, including a well‐defined stacking structure, high porosity, and a substantial specific surface area, making it suitable as an active ...
Akash Sivanandan+5 more
wiley +1 more source
Influence of nicotine and alcohol on sleep latency: the reward-attention circuit model [PDF]
We previously developed a neurocomputational model called the reward-attention circuit, which has been used to investigate the separate effects of nicotine and alcohol on attention focus. The model is based on known circuits linking midbrain dopaminergic neurons to the thalamocortical loop and is sufficiently versatile to capture diverse phenomena.
arxiv
Structurally similar allosteric modulators of α7 nicotinic acetylcholine receptors exhibit five distinct pharmacological effects. [PDF]
Activation of nicotinic acetylcholine receptors (nAChRs) is associated with the binding of agonists such as acetylcholine to an extracellular site that is located at the interface between two adjacent receptor subunits.
D'Oyley, JM+4 more
core
Periodontitis presenting among betel quid users: A case series
Abstract Background Betel leaf chewing habit has been studied extensively, as it has been an ancient practice in many Asian countries. Although betel leaf has been reported to have potential beneficial properties, it has also been shown to have a strong association with oral diseases, including periodontitis. This case series addresses the presentation
Jungweon V. Park+2 more
wiley +1 more source
Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man1
The mechanisms for the hypolipidemic action of nicotinic acid were examined in 12 patients with hyperlipidemia. Most patients were studied in the hospital on a metabolic ward.
S M Grundy, H Y Mok, L Zech, M Berman
doaj
Effect of E-cigarette Use and Social Network on Smoking Behavior Change: An agent-based model of E-cigarette and Cigarette Interaction [PDF]
Despite a general reduction in smoking in many areas of the developed world, it remains one of the biggest public health threats. As an alternative to tobacco, the use of electronic cigarettes (ECig) has been increased dramatically over the last decade. ECig use is hypothesized to impact smoking behavior through several pathways, not only as a means of
arxiv