Results 121 to 130 of about 60,107 (283)

Comparative efficacy of novel bioactive glass versus sodium fluoride toothpaste for dentin hypersensitivity

Journal of Periodontology, EarlyView.
Abstract Background This first‐in‐human clinical study aimed to evaluate the safety and efficacy of a bioglass incorporated in a toothpaste, in reducing dentin hypersensitivity (DH) compared to a sodium fluoride (NaF) toothpaste over a 2‐week period. Methods A double‐blind, randomized, parallel‐arm, proof‐of‐concept clinical trial was conducted with 46
Hatice Hasturk, Daniel Boyd, Kathleen MacDonald‐Parsons, Stephanie Turner‐Cahill, Joon Seong, Nicola West, Heather J. Doucette   +6 more
wiley   +1 more source

Twenty‐four month clinical outcomes of modified coronally advanced tunnel technique with leukocyte‐ and platelet‐rich fibrin–functionalized porcine dermal matrix for single/multiple gingival recessions

Journal of Periodontology, EarlyView.
Abstract Background To report 24‐month clinical and 3D outcomes of single and multiple RT1 and RT2 gingival recessions treated with the modified coronally advanced tunnel (MCAT) technique and an L‐PRF‐functionalized porcine dermal matrix (PDM), as long‐term data on PDM in root coverage are scarce.
Erik Würflein, Katharina Herrmann, Anton Sculean, Kirstin Vach, Katja Nelson, Tobias Fretwurst, Gerhard Iglhaut, Florian Kernen   +7 more
wiley   +1 more source

Effect of nicotinic acid supplementation on digestion, metabolism, microbiome, and production in late-lactation Holstein cows

Journal of Dairy Science
: The purpose of this experiment was to determine if nicotinic acid (NA) effects on dairy cows and rumen microbial characteristics are forage-type dependent (corn silage, CS; grass silage, GS).
R.B. Standish, A.D. Wright, N.L. Whitehouse, P.S. Erickson   +3 more
doaj   +1 more source

Peri‐ and Post‐Menopausal Hormone Replacement Therapy and Voice Disorder Risk: A TriNetX Study

The Laryngoscope, EarlyView.
ABSTRACT Objectives The aim of this study was to elucidate the risk of developing voice disorders among peri‐ and post‐menopausal female hormone replacement therapy (HRT) users. Methods A retrospective cohort study was conducted using the TriNetX Global Collaborative Network.
David Kayekjian, Warren B. Chun, Shaun A. Nguyen, Ashli K. O'Rourke, Kirsten D. Meenan   +4 more
wiley   +1 more source

Higher Increases in Plasma n‐3 Polyunsaturated Fatty Acids Following Fish Oil Supplementation in Postmenopausal Females Compared With Age‐Matched Males

Lipids, EarlyView.
ABSTRACT The effects of fish oil supplementation on omega‐3 (n‐3) polyunsaturated fatty acids, particularly intermediates between eicosapentaenoic acid (EPA, 20:5n‐3) and docosahexaenoic acid (DHA, 22:6n‐3), that may provide valuable metabolic information, have not been fully characterized in older populations.
David C. R. Ku, Insaf Loukil, Annick Vachon, Mélanie Plourde, Adam H. Metherel   +4 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Nicotinic Acid [PDF]

Nature, 1972
openaire   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

Pest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks, Tom W. Pope, Simon Cooper, Joe M. Roberts   +3 more
wiley   +1 more source