Results 121 to 130 of about 65,529 (332)
Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation. [PDF]
, 1996 Agrin is thought to be the nerve-derived factor that initiates acetylcholine receptor (AChR) clustering at the developing neuromuscularjunction. We have investigated the signaling pathway in mouse C2 myotubes and report that agrin induces a rapid but ...
Deiner, M, Ferns, M, Hall, Z
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Mass Spectrometry Reviews, EarlyView.ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo +5 more
wiley +1 more source
Vagus Nerve Stimulation in Movement Disorders, from Principles to a Systematic Review of Evidence
Movement Disorders, EarlyView.Abstract Background The vagus nerve (VN), the principal component of the parasympathetic branch of the autonomic nervous system (ANS), mediates bidirec communication between the central nervous system (CNS) and peripheral organs. Vagus nerve stimulation (VNS), delivered through invasive (iVNS) or non‐invasive (transcutaneous cervical [tcVNS] and ...
Francesca Proietti +9 more
wiley +1 more source
EFFECT OF 2,4-DICHLOROPHENOXYACETIC ACID ON THE CONTENT OF THIAMINE, RIBOFLAVIN, NICOTINIC ACID, PANTOTHENIC ACID AND CAROTENE IN STEMS AND LEAVES OF RED KIDNEY BEAN PLANTS [PDF]
, 1949 R. W. Luecke +2 more
openalex +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg +3 more
wiley +1 more source
Molecular Nutrition &Food Research, EarlyView.Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
Carmen García‐Ruano +3 more
wiley +1 more source
Uniquely human CHRFAM7A gene increases the hematopoietic stem cell reservoir in mice and amplifies their inflammatory response. [PDF]
, 2019 A subset of genes in the human genome are uniquely human and not found in other species. One example is CHRFAM7A, a dominant-negative inhibitor of the antiinflammatory α7 nicotinic acetylcholine receptor (α7nAChR/CHRNA7) that is also a neurotransmitter ...
Baird, Andrew +7 more
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Pediatric Discovery, EarlyView.Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Observations on the Curative Effect of Nicotinic Acid and of Liver in the Canine Black Tongue Disease1 [PDF]
, 1938 R Nicolaysen, Per Laland
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The surface accessibility of α-bungarotoxin monitored by a novel paramagnetic probe [PDF]
, 2011 The surface accessibility of {alpha}-bungarotoxin has been investigated by using Gd2L7, a newly designed paramagnetic NMR probe. Signal attenuations induced by Gd2L7 on {alpha}-bungarotoxin C{alpha}H peaks of 1H-13C HSQC spectra have been analyzed and ...
Bernini, A +7 more
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