Results 121 to 130 of about 5,143,045 (401)
The effect of 3-indoleacetic acid on the response of Lactobacillus arabinosus 17-5 to nicotinamide [PDF]
, 1949 Lactobacillus arabinosus 17-5 has been widely used as an assay organism for nicotinic acid (NA) since the development of the method by Snell and Wright (1). Although it has been realized that other substances present in tissue extracts may interfere with
Galston, Arthur W., Hand, Margery E.
core
Chronic Diseases and Translational Medicine, EarlyView.Donanemab, approved by the U.S. FDA in July 2024, targets amyloid plaques in the brain to treat Alzheimer's disease in patients with mild cognitive impairment or mild dementia. ABSTRACT Substantial research has been conducted to identify an efficient treatment for Alzheimer's disease (AD).
Nandhini Jayaprakash +1 more
wiley +1 more source
A physical model of nicotinic ACh receptor kinetics [PDF]
arXiv, 2008 We present a new approach to nicotinic receptor kinetics and a new model explaining random variabilities in the duration of open events. The model gives new interpretation on brief and long receptor openings and predicts (for two identical binding sites) the presence of three components in the open time distribution: two brief and a long.
arxiv
Alcohol and Carbonyl Redox Reactions in Electrochemical Organic Synthesis
ChemistryEurope, EarlyView.This review aims to provide the reader with a useful tool to deal with electrochemical redox reactions involving alcohols and carbonyl compounds. The review is organized in an accessible format and divided into sections that focus on key parameters of wide‐ranging electrosynthetic methods.
Fiammetta Vitulano +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior [PDF]
, 2003 Prenatal nicotine exposure has been linked to attention deficit hyperactivity disorder and cognitive impairment, but the sites of action for these effects of nicotine are still under investigation. High-affinity nicotinic acetylcholine receptors (nAChRs)
Caldarone, Barbara J +7 more
core +2 more sources
Experimental Biology and Medicine, 1938 SummaryNicotinic acid is at least several hundred times less toxic in mice, rats, and guinea pigs than nicotine. Nicotinic acid is devoid of action upon the autonomic ganglia. Nevertheless, repeated administration of large doses, 2 gm. daily, in dogs has resulted in poisoning and deaths.
Charles L. Rose +2 more
openaire +2 more sources
Chemistry–Methods, EarlyView.Limits of detection and quantification of fluorinated analytes by 19F benchtop (1 T) NMR spectroscopy in the high nanomolar to low micromolar range are achieved using signal amplification by reversible exchange (SABRE) combined with the multiplet‐refocusing technique, SHARPER (Sensitive, Homogeneous, And Resolved PEaks in Real time).
Ana I. Silva Terra, Meghan E. Halse
wiley +1 more source
Química Nova, 2011 This work describes the creation of an very simple calculation algorithm, based in basic chemical and mathematic principles, for the calculation of weak diprotic acid dissociation constants as, for example, amino acids, from potentiometric titrations ...
Elsa M. Gonçalves +1 more
doaj +1 more source
Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta [PDF]
, 2017 Preventive chemotherapy has long been practiced against nematode parasites of livestock, leading to widespread drug resistance, and is increasingly being adopted for eradication of human parasitic nematodes even though it is similarly likely to lead to ...
Bisset, Stewart A +6 more
core +3 more sources