Results 141 to 150 of about 5,143,045 (401)
The reductive hydroformylation of linseed oil was carried out using a rhodium precursor associated with various nitrogen derivatives such as pyridines, imidazoles, trialkylamines, amidines, and guanidines. ABSTRACT The reductive hydroformylation reaction of polyunsaturated linseed oil using a rhodium precursor associated with a nitrogen compound from ...
Walid Abdallah+9 more
wiley +1 more source
NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly
Summary: The α7 nicotinic acetylcholine receptor participates in diverse aspects of brain physiology and disease. Neurons tightly control α7 assembly, which relies upon NACHO, an endoplasmic reticulum (ER)-localized integral membrane protein.
Hae-Jin Kweon+7 more
doaj
Is Amino-Acid Homochirality Due To Asymmetric Photolysis In Space? [PDF]
Amino acids occurring in proteins are, with rare exceptions, exclusively of the L-configuration. Among the many scenarios put forward to explain the origin of this chiral homogeneity (i.e., homochirality), one involves the asymmetric photolysis of amino acids present in space, triggered by circularly polarized UV radiation.
arxiv
Age-related increase of kynurenic acid in human cerebrospinal fluid-IgG and beta(2)-microglobulin changes [PDF]
Kynurenic acid (KYNA) is an endogenous metabolite in the kynurenine pathway of tryptophan degradation and is an antagonist at the glycine site of the N-methyl-D-aspartate as well as at the alpha 7 nicotinic cholinergic receptors. In the brain tissue KYNA
Baran, H+5 more
core
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang+3 more
wiley +1 more source
Are Strong Bronsted Acids Necessarily Strong Lewis Acids? [PDF]
The Broensted and Lowry acid base theory is based on the capacity of proton donation or acceptance (in the presence or absence of a solvent) whereas the Lewis acid base theory is based on the propensity of electron pair acceptance or donation. We explore through DFT calculation the obvious question whether these two theories are in conformity with each
arxiv
Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz+4 more
wiley +1 more source
This article is devoted to discussion about main aspects of current use of non-statin hypolipidemic drugs according last international guidelines (including fibrates, nicotinic acid, resins, polyunsaturated fatty acids, ezetimibe, PCSK9-inhibitors).
A. E. Bagriy+6 more
doaj
The term ‘niacin’ is used as generic description of nicotinic acid and nicotinamide with pyridine as the basic structure. Nicotinic acid and nicotinamide function mainly as precursors of the co‐enzymes NAD and NADP. Thus, nicotinamide has physiologically
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj +1 more source
The Factors of the Classification of Protein Amino Acids [PDF]
In this work it is shown that three pairs of the factors appear to be the key, i.e. main factors of a natural classification of protein (canonical) amino acids within the amino acid (genetic) code. First pair: the factors of the habit of an amino acid molecule (size and polarity).
arxiv