Results 171 to 180 of about 65,529 (332)

Nicotinic Acid as a Growth Accessory Substance for the Diphtheria Bacillus [PDF]

, 1937
J. Howard Mueller
openalex   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

THE EFFECT OF TRYPTOPHANE ON THE EXCRETION OF NICOTINIC ACID DERIVATIVES IN HUMANS

, 1947
Herbert P. Sarett, Grace A. Goldsmith
openalex   +1 more source

The destruction of isonicotinic acid hydrazide in the presence of haemin [PDF]

, 1955
Adrien Albert, Charles W. Rees
openalex   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Nicotinic Acid Therapy of Dermatitis Herpetiformis

, 1950
H. H. Johnson, G.W. Binkley
openalex   +1 more source

Genetic variants linked to statin‐associated Type 2 diabetes mellitus: Findings from the UK Biobank and the All of Us Research Program

British Journal of Pharmacology, EarlyView.
Background and Purpose Statins are widely prescribed for the prevention of cardiovascular disease, yet recent studies suggest an increased risk of new‐onset Type 2 diabetes mellitus. This study aimed to identify genetic variants associated with statin‐associated new‐onset Type 2 diabetes mellitus from the UK Biobank and All of Us.
Yoon‐A Park, Da Hoon Lee, Jung Sun Kim, Jeong Yee, Hye Sun Gwak   +4 more
wiley   +1 more source

Microbial Intervention in the Soaking Step during Tempeh Preparation to Modulate B Vitamin Contents: A Metabolomics Approach. [PDF]

Prev Nutr Food Sci
Riyanto RA, Fukusaki E, Putri SP.
europepmc   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Application of Organic Nanofibers to Boost Specialized Metabolite Production and Antioxidant Potential in <i>Stevia rebaudiana</i> In Vitro Cultures. [PDF]

Metabolites
Geneva M, Trendafilova A, Miladinova-Georgieva K, Sichanova M, Tsekova D, Ivanova V, Kirova E, Petrova M.   +7 more
europepmc   +1 more source