Results 171 to 180 of about 5,143,045 (401)

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Sequencing of rabies binding region on nicotinic acteylcholine receptor alpha subunits in four host species [PDF]

open access: yes, 2013
• Rabies virus is known to bind to nicotinic acetylcholine receptors (nAchR) • The virus is known to bind to alpha 1 subunits nAchR • The virus binding region has been characterized in alpha 1 subunits of these receptors • Little research has been ...
Barnard, Karen
core  

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo   +5 more
wiley   +1 more source

Reactivity of Imidazole‐ and Pyridine‐Carboxaldehydes for Gem‐Diol and Hemiacetal Generation: Theoretical and Experimental Insights

open access: yesChemistryOpen, EarlyView.
The generation of the gem‐diol and hemiacetal forms using pyridine‐ and imidazole‐carboxaldehyde isomers in different chemical environments was studied by NMR spectra and combined with theoretical calculations. Unlike aprotic solvents, protic ones, as water and methanol, favored the generation of the gem‐diol and hemiacetal structures.
Ayelén F. Crespi   +5 more
wiley   +1 more source

Dosing profile profoundly influences nicotinic acid's ability to improve metabolic control in rats

open access: yesJournal of Lipid Research, 2015
Acute nicotinic acid (NiAc) administration results in rapid reduction of plasma FFA concentrations. However, sustained NiAc exposure is associated with tolerance development resulting in return of FFA to pretreatment levels.
Tobias Kroon   +4 more
doaj  

Reaction of Ethylene Oxide with Nicotinamide and Nicotinic Acid

open access: hybrid, 1959
H.G. Windmueller   +3 more
openalex   +1 more source

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