Results 181 to 190 of about 28,584 (243)

Development of plant‐derived biomimetic nanoparticles as a novel targeted drug delivery platform

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Plant‐derived biomimetic nanoparticles (PD‐BNPs) represent a sustainable and biocompatible nanoplatform for targeted drug delivery. This review highlights their therapeutic potential, engineering strategies, and translational challenges toward precision nanomedicine applications. Abstract Plant‐derived biomimetic nanoparticles (PD‐BNPs) have emerged as
Jihad Hasan, Asnaf Nihan Shuvo, Md. Rezaul Karim Sheikh, A. Nayeem Faruqui   +3 more
wiley   +1 more source

Effects of Swapping 5HT3 and α7 Residues in Chimeric Receptor Proteins on RIC3 and NACHO Chaperone Actions. [PDF]

Molecules
Yan Z, Oruganti S, Iyer SK, Agarwal K, Gupta M, Adhikari K, Vijayan N, Doda J, Jain V, Lokhande AN, Nair AP, Nallanichakravarthula VSK, Weltzin MM, Loring RH.   +13 more
europepmc   +1 more source

Structure‐Based Design, Synthesis, and Biological Evaluation of Oxadiazole–Morpholine Hybrids as Potent PARP‐1 Inhibitors Inducing Apoptosis in Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Poly(ADP‐ribose) polymerase‐1 (PARP‐1) plays a central role in the repair of DNA single‐strand breaks and represents an established therapeutic target in cancer treatment. In this study, a series of novel oxadiazole–morpholine hybrid compounds was designed and synthesized using a structure‐based drug design approach to target the catalytic ...
Nader R. Albujuq, Khaled M. Darwish, Sherif Ashraf Fahmy, Buthaina Hussein, Ghada G. Kayed, Musa A. Said, Mohamed S. Nafie   +6 more
wiley   +1 more source

Nutrition in the prevention and treatment of pelvic inflammatory disease: a review. [PDF]

Front Nutr
Wang G, Zhang S.
europepmc   +1 more source

Discovery of a Potent and Selective MAO‐B Inhibitor From a Donepezil‐Linked Chalcone Library With Promising Antiparkinsonian Activity

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A focused library of 19 donepezil‐linked chalcones (DLCs) was efficiently synthesised through microwave‐assisted Claisen‐Schmidt condensation and subsequently profiled for their inhibitory activities against cholinesterases (AChE and BuChE) as well as monoamine oxidases (MAO‐A and MAO‐B).
Azize Kirac‐Aydin, Bishnu Prasad Pandey, Satyajit Mohanty, Rupsa Mondal, Abanish Biswas, Ashok Kumar Pattnaik, Subodh Mondal, Vinay N. Basavanakatti, Nilüfer Bayrak, Venkatesan Jayaprakash, Hoon Kim, Amaç Fatih TuYuN   +11 more
wiley   +1 more source

Metabolic modeling links gut microbiota to metabolic markers of Parkinson's disease. [PDF]

Gut Microbes
Hensen T, Thiele I.
europepmc   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

International Journal of Gynecology &Obstetrics, Volume 174, Issue 2, Page 718-729, August 2026.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source

Ethanolic Extract of <i>Stachys byzantina</i> Leaf: Optimization of Ultrasonic Probe-Assisted Extraction and Characterization. [PDF]

Plants (Basel)
Dias SLG, Raspe DT, Júnior OOS, Agneis MLG, Seiva FRF, Garcia VADS, Cardozo-Filho L, Silva CD.   +7 more
europepmc   +1 more source

HSV1 glycoprotein D utilizes an LY6-like binding domain to inhibit alpha7 nicotinic receptors. [PDF]

Npj Viruses
Yeasmin S, Sharma K, Nicolet C, DeCristofano L, Ataian Y, Ranjit A, Aghazadeh-Habashi A, Xu D, Schulte M.   +8 more
europepmc   +1 more source

Shikimate crosstalk enables record-level homogentisic acid production in <i>Yarrowia lipolytica</i>. [PDF]

Synth Syst Biotechnol
Xu C, Zhang W, Zhao Q, Lin X, Wang K, Wang M, Tan T.   +6 more
europepmc   +1 more source