Results 201 to 210 of about 5,143,045 (401)

Age‐Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light‐Induced Outer Retinal Degeneration in Mice

open access: yesAging Cell, EarlyView.
Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox   +13 more
wiley   +1 more source

HYPERTRIGLYCERIDEMIC ACUTE PANCREATITIS: PROGRESS AND PROBLEMS

open access: yesАтеросклероз, 2017
The purpose of the review. Analyze basic data on the hypertrigliceridemia (HTG) role in the pathogenesis of HTG-associated acute pancreatitis (AP), and the current treatment of the disease. Recent literature data.
I. N. Grigorieva
doaj  

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

open access: yesAging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji   +15 more
wiley   +1 more source

NICOTINIC ACID METABOLISM

open access: hybrid, 1957
Mei Ling Chang, B. Connor Johnson
openalex   +1 more source

Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2008
G. Young   +4 more
semanticscholar   +1 more source

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