Results 111 to 120 of about 2,143 (224)
Molecular Pain, 2011 Background TC-2559 is a selective α4β2 subtype of nicotinic acetylcholine receptor (nAChR) partial agonist and α4β2 nAChR activation has been related to antinociception.
Peng Li-Chao +5 more
doaj +1 more source
THE EFFECT OF TUBOCURARINE COMPETITION ON THE KINETICS OF AGONIST ACTION ON THE NICOTINIC RECEPTOR [PDF]
, 1982 David Colquhoun, Robert E. Sheridan
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British Journal of Pharmacology, EarlyView.Background and Purpose Platelet function during inflammation is dependent on activation by endogenous nucleotides acting on purinergic receptors. The P2Y14 receptor has been reported to be expressed on platelets and is involved in leukocyte recruitment during inflammation.
Md Monir Hossain +6 more
wiley +1 more source
Cell Proliferation, EarlyView.Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin +4 more
wiley +1 more source
Nicotinic agonists antagonize quantal size increases and evoked release at frog neuromuscular junction. [PDF]
, 1993 W. Van der Kloot
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Macrophages and autophagy: partners in crime
The FEBS Journal, EarlyView.Autophagy is a key regulator of macrophage function, influencing critical processes like polarization, cytokine secretion, and phagocytosis. Its impact on macrophage behavior varies across different tissues and disease contexts, where it can either promote protective responses or contribute to detrimental outcomes, depending on the physiological or ...
Alessandra Vitaliti +2 more
wiley +1 more source
Pharmacological Characterization of RJR‐2403: A Nicotinic Agonist with Potential Therapeutic Benefit in the Treatment of Alzheimer's Disease [PDF]
, 1997 Merouane Bencherif +4 more
openalex +1 more source
The FEBS Journal, EarlyView.Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti +9 more
wiley +1 more source
d‐amino acids: new functional insights
The FEBS Journal, EarlyView.This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni +5 more
wiley +1 more source
The effects of Nicotine on licking behavior induced by Apomorphine in rats
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 1999 Objective: The purpose of the present study was to determine the possible interaction of nicotine or muscarinic receptor mechanism(s) with the licking behavior induced by apomorphine in rats.
MR Zarrindast, M Shecharchi, M Rezayat
doaj