Results 131 to 140 of about 41,031 (306)
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Channel blocking properties of a series of nicotinic cholinergic agonists
Inhibition of the nicotinic acetylcholine receptor (nAChR) by channel blockade has been demonstrated with a variety of large organic cations, including several nicotinic agonists. We have studied the kinetics of channel blocking of a series of agonists which vary systematically in size and hydrophobicity due to a hydrocarbon chain from one to six ...
Robert E. Oswald, Alison A. Carter
openaire +3 more sources
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
THE EFFECT OF TUBOCURARINE COMPETITION ON THE KINETICS OF AGONIST ACTION ON THE NICOTINIC RECEPTOR [PDF]
David Colquhoun, Robert E. Sheridan
openalex +1 more source
Role of nicotine receptor partial agonists in tobacco cessation
One in three adults in India uses tobacco, a highly addictive substance in one or other form. In addition to prevention of tobacco use, offering evidence-based cessation services to dependent tobacco users constitutes an important approach in addressing this serious public health problem.
Pratima Murthy +2 more
openaire +3 more sources
Animal medical systems from Apis to apes: history, recent advances and future perspectives
ABSTRACT Animal medical systems encompass a wide range of behaviours aimed at maintaining or improving health. It has become clear that these behaviours are not limited to animals treating themselves (self‐medication) but also include the treatment of group members, resulting in the adoption of the more inclusive term “animal medication”.
Michelina Pusceddu +5 more
wiley +1 more source
Nicotine exposure is a risk factor in several breathing disorders Nicotinic acetylcholine receptors (nAChRs) exist in the ventrolateral medulla, an important site for respiratory control.
EIKI HATORI +7 more
doaj
Abstract Aims To evaluate whether weight‐loss interventions are associated with obesity‐associated cancers (OAC) in individuals with overweight/obesity and type 2 diabetes (T2D). Materials and Methods This retrospective cohort study utilised the TriNetX federated research network.
Testimony Ipaye +7 more
wiley +1 more source
Abstract Aims There is growing evidence that the GLP‐1 system is implicated in alcohol and other substance use disorders, and that GLP‐1‐based therapies may have therapeutic relevance in alcohol use disorder (AUD). We aimed to determine the impact of GLP‐1 based therapies on incident AUDs in a real‐world setting in patients with T2D.
Alex E. Henney +8 more
wiley +1 more source
Nicotinic agonists antagonize quantal size increases and evoked release at frog neuromuscular junction. [PDF]
W. Van der Kloot
openalex +1 more source

