Results 131 to 140 of about 2,143 (224)
Abstract Doppler ultrasound may be used to assess leg blood flow (Q̇leg${{\dot{Q}}_{{\mathrm{leg}}}}$), but the reliability of this method remains unexplored in patients with chronic obstructive pulmonary disease (COPD), where between‐subject variability may be larger than healthy due to peripheral vascular changes.
Milan Mohammad+5 more
wiley +1 more source
Isoflurane Increases the Apparent Agonist Affinity of the Nicotinic Acetylcholine Receptor by Reducing the Microscopic Agonist Dissociation Constant [PDF]
Douglas E. Raines, Vinu T. Zachariah
openalex +1 more source
Abstract figure legend The carotid body develops aberrant high activity in chronic heart failure, resistant hypertension, obstructive sleep apnoea (OSA) and diabetes. Hyperactivity of the carotid body leads to both high tonicity and increased sensitivity of the arterial chemoreflex with resultant sympathoexcitation.
Tymoteusz Żera+7 more
wiley +1 more source
Preclinical Pharmacology of ABT‐594: A Nicotinic Acetylcholine Receptor Agonist for the Treatment of Pain [PDF]
Michael D. Meyer+6 more
openalex +1 more source
Cyto‐Genotoxic Assessment of Sulfoxaflor in Allium cepa Root Cells and DNA Docking Studies
Cyto‐genotoxic Assessment of Sulfoxaflor in Allium cepa Root Cells and DNA Docking Studies. ABSTRACT Sulfoxaflor (SFX) is an insecticide that is commonly used for the control of sap‐feeding insects. Since SFX is extensively applied globally, it has been implicated in the substantial induction of environmental toxicity.
Recep Liman+7 more
wiley +1 more source
Contributions of Torpedo Nicotinic Acetylcholine Receptor γTrp-55 and δTrp-57 to Agonist and Competitive Antagonist Function [PDF]
Yu Xie, Jonathan B. Cohen
openalex +1 more source
GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases
Within the GABAergic system, GABABRs are potential therapeutic targets for dealing multiple metabolic and binge eating disorders and food addiction. Allosteric modulators and small peptides targeting GABABR signaling pathways may be developed as attractive drug candidates that avoid the side effects of agents that directly bind these receptors ...
Weijie Xie+10 more
wiley +1 more source
The Calcium Sensor Protein Visinin-like Protein-1 Modulates the Surface Expression and Agonist Sensitivity of the α4β2 Nicotinic Acetylcholine Receptor [PDF]
Lin Lin+5 more
openalex +1 more source
ABSTRACT Iatrogenic nerve injuries are a significant concern for medical professionals and the patients affected. Peri‐procedural nerve injuries result in functional deficits associated with pain and disability. The exact pathophysiology and etiology of peri‐procedural nerve injuries are complex and often elude providers.
Geoffrey K. Seidel+7 more
wiley +1 more source