Enteric neuropathy and the vagus nerve: Therapeutic implications
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley +1 more source
AGONIST-INDUCED AFFINITY ALTERATIONS OF A CENTRAL NERVOUS SYSTEM NICOTINIC ACETYLCHOLINE RECEPTOR
Ronald J Lukasiewicz, Edward L Bennett
openalex +1 more source
Agonist-induced hump current production in heterologously-expressed human α4β2-nicotinic acetylcholine receptors [PDF]
Qiang Liu+4 more
openalex +1 more source
Abstract Survival relies on neural respiratory drive from the medullary respiratory centres to activate the respiratory muscles for breathing. Accurate assessment of respiratory muscle activity, as an estimate of neural respiratory drive in humans, will facilitate a greater understanding of respiratory physiology, the pathophysiology of diseases and ...
Anna L. Hudson+3 more
wiley +1 more source
Effects of NPY and the specific Y1 receptor agonist [d-His26]-NPY on the deficit in brain reward function and somatic signs associated with nicotine withdrawal in rats [PDF]
Daria Rylkova+5 more
openalex +1 more source
Atypical nicotinic agonist bound conformations conferring subtype selectivity
M. Tomizawa+7 more
semanticscholar +1 more source
HSV1 glycoprotein D utilizes an LY6-like binding domain to inhibit alpha7 nicotinic receptors. [PDF]
Yeasmin S+8 more
europepmc +1 more source
During endothelial cell Ca2+ wave propagation, IP3 in the initiating cell activates IP3Rs on the endoplasmic reticulum, releasing Ca2+ into the cytoplasm. We show that IP3 is required for signal propagation to neighboring cells and propose that this is due to activation of membrane‐bound pore‐dead IP3Rs, as part of a noncanonical signaling inside‐out ...
C. Buckley+4 more
wiley +1 more source
Stereoisomers of Chiral Methyl-Substituted Symmetric and Asymmetric Aryl Piperazinium Compounds Exhibit Distinct Selectivity for α9 and α7 Nicotinic Acetylcholine Receptors. [PDF]
Andleeb H+8 more
europepmc +1 more source