Results 221 to 230 of about 481,268 (346)

Modulation of airway inflammation and resistance in mice by a nicotinic receptor agonist [PDF]

, 2005
M-R. Blanchet, Évelyne Israël-Assayag, Yvon Cormier   +2 more
openalex   +1 more source

Metabolomics in cardiometabolic diseases: Key biomarkers and therapeutic implications for insulin resistance and diabetes

Journal of Internal Medicine, Volume 297, Issue 6, Page 584-607, June 2025.
Abstract Cardiometabolic diseases—including Type 2 diabetes and obesity—remain leading causes of global mortality. Recent advancements in metabolomics have facilitated the identification of metabolites that are integral to the development of insulin resistance, a characteristic feature of cardiometabolic disease. Key metabolites, such as branched‐chain
David Rizo‐Roca, John D. Henderson, Juleen R. Zierath   +2 more
wiley   +1 more source

The characterization of a novel rigid nicotine analog with α7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion [PDF]

, 2005
Roger L. Papke, Guangrong Zheng, Nicole A. Horenstein, Linda P. Dwoskin, Peter A. Crooks   +4 more
openalex   +1 more source

Functional Magnetic Resonance Imaging of Effects of a Nicotinic Agonist in Schizophrenia

Neuropsychopharmacology, 2010
J. Tregellas, A. Olincy, L. Johnson, J. Tanabe, Shireen Shatti, Laura F. Martin, D. Singel, Yiping P. Du, F. Soti, W. Kem, R. Freedman   +10 more
semanticscholar   +1 more source

Autonomic Nervous System in Bone Remodeling: From Mechanisms to Novel Therapies in Orthopedic Diseases

Orthopaedic Surgery, Volume 17, Issue 6, Page 1561-1576, June 2025.
Due to the close connection between the autonomic nervous system and skeletal system, large amounts of evidence have shown that neuromodulation plays a crucial role in regulating bone metabolism. Clinically, neuromodulation has exhibited promising therapeutic effects in treating joint disorders by significantly reducing inflammation and clinical scores.
Ruihao Xia, Hongjun Peng, Xishan Zhu, Wangdui Suolang, Steve T. L. Pambayi, Xiao Yang, Yi Zeng, Bin Shen   +7 more
wiley   +1 more source

Recent Advances in the α‐Hydrazination (α‐Amination) of Carbonyl Compounds

European Journal of Organic Chemistry, Volume 28, Issue 17, May 21, 2025.
In recent years, notable progress has been achieved in the α‐hydrazination (α‐amination) of carbonyl compounds, especially in the direct asymmetric electrophilic α‐hydrazination with dialkyl azodicarboxylates. This review summarizes all the methods that appeared over the past decade, categorized based on the type of the reactive chiral intermediate ...
Dina Scarpi, Samuele Visi, Ernesto G. Occhiato   +2 more
wiley   +1 more source

Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation: A Randomized Controlled Trial—Correction [PDF]

, 2006

openalex   +1 more source

Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats. [PDF]

Psychopharmacology (Berl), 2018
Maggio SE, Saunders MA, Baxter TA, Nixon K, Prendergast MA, Zheng G, Crooks P, Dwoskin LP, Slack RD, Newman AH, Bell RL, Bardo MT.   +11 more
europepmc   +1 more source

Preclinical pharmacology, efficacy, and safety of varenicline in smoking cessation and clinical utility in high risk patients

Drug, Healthcare and Patient Safety, 2010
Zheng-Xiong XiNational Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USAAbstract: Smoking is still the most prominent cause of preventable premature death in the United States and an increasing cause of morbidity and mortality ...
Zheng-Xiong Xi
doaj  

Effect of ABT-594 a Selective Nicotinic Agonist, on Voiding Function in Spinal Cord Injury Rat [PDF]

, 2006
Hyun Rho, Sun-Ju Lee, Sung‐Goo Chang
openalex   +1 more source