Results 21 to 30 of about 2,143 (224)
Marine Drugs, 2015 6-Bromohypaphorine (6-BHP) has been isolated from the marine sponges Pachymatisma johnstoni, Aplysina sp., and the tunicate Aplidium conicum, but data on its biological activity were not available.
Igor E. Kasheverov +7 more
doaj +1 more source
Soil nematode Caenorhabditis elegans Maupas as a convenient model organism to study anthelmintic activity of plant extracts [PDF]
E3S Web of Conferences, 2020 The article deals with the study of the possibility to use free-living soil nematode C. elegans in researches of anthelmintic activity of plant raw material. A. sativum juice and aqueous extract of T. vulgare flowers were used in experiments. It is shown
Egorova Anastasia +4 more
doaj +1 more source
Molecular adsorption study of nicotine and caffeine on the single-walled carbon nanotube from first principles [PDF]
Solid State Communications, v.167, pp.27 - 30 (2013), 2012 Using first-principles calculations, we investigate the electronic structures and binding properties of nicotine and caffeine adsorbed on single-walled carbon nanotubes to determine whether CNTs are appropriate for filtering or sensing nicotine and caffeine molecules. We find that caffeine adsorbs more strongly than nicotine.
arxiv +1 more source
Angewandte Chemie, EarlyView.Tetra‐ortho‐Azobenzenes (TOABs) in broad daylight: in recent years, TOAB photoswitches became indispensable tools for all‐visible‐light manipulation of chemistry, biology and materials. This review explores their unique photochemical properties, design and synthetic approaches, offering support in choosing a TOAB for a given application.
Francesca Cardano +2 more
wiley +2 more sources
The effect of amixin and agmatine on cytochrome c release from isolated mitochondria [PDF]
The Ukrainian Biochemical Journal, 2017 Mitochondrial nicotinic acetylcholine receptors (nAChRs) control permeability transition pore formation and cytochrome c release in the presence of apoptogenic factors.
K. R. Uspenska +3 more
doaj +1 more source
Single Molecule Transistor based Nanopore for the detection of Nicotine [PDF]
Journal of Applied Physics 116, 244307 (2014), 2015 A nanopore based detection methodology was proposed and investigated for the detection of Nicotine. This technique uses a Single Molecular Transistor (SMT) working as a nanopore operational in the Coulomb Blockade regime. When the Nicotine molecule is pulled through the nanopore area surrounded by the Source(S), Drain(D) and Gate electrodes, the charge
arxiv +1 more source
The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits. [PDF]
PLoS Pathogens, 2009 Parasitic nematodes are of medical and veterinary importance, adversely affecting human health and animal welfare. Ascaris suum is a gastrointestinal parasite of pigs; in addition to its veterinary significance it is a good model of the human parasite ...
Sally M Williamson +7 more
doaj +1 more source
Agonist activation of a nicotinic acetylcholine receptor [PDF]
Neuropharmacology, 2015 How does an agonist activate a receptor? In this article I consider the activation process in muscle nicotinic acetylcholine receptors (AChRs), a prototype for understanding the energetics of binding and gating in other ligand-gated ion channels. Just as movements that generate gating currents activate voltage-gated ion channels, movements at binding ...
openaire +3 more sources
Silent agonists for α7 nicotinic acetylcholine receptors
Pharmacological Research, 2023 We discuss models for the activation and desensitization of α7 nicotinic acetylcholine receptors (nAChRs) and the effects of efficacious type II positive allosteric modulators (PAMs) that destabilize α7 desensitized states. Type II PAMs such as PNU-120596 can be used to distinguish inactive compounds from silent agonists, compounds that produce little ...
Roger L. Papke +2 more
openaire +3 more sources
, 2022 CPT: Pharmacometrics &Systems Pharmacology, Volume 11, Issue 12, Page 1556-1559, December 2022.
Ronald Gieschke, Robert Carr
wiley +1 more source