Results 31 to 40 of about 41,965 (298)
Cholinergic mechanisms in supramammillary nucleus (SuM), especially the lateral SuM (lSuM) modulates septo-hippocampal neural activity. The lSuM, as compared to the contiguous medial SuM (mSuM) has relatively dense projections to hippocampus and ...
Mohammed Z. Ariffin +4 more
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Cholinergic modulation of dopamine overflow in the rat neostriatum: A fast cyclic voltammetric study in vitro [PDF]
Stimulus-evoked dopamine overflow in rat neostriatal slices was determined using fast cyclic voltammetry. The dopamine efflux induced by intrastriatal stimulation increased with stimulus intensity and was found to be enhanced by more than 100% upon ...
Kudernatsch, Martina, Sutor, Bernd
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1,2,3,4-Tetrahydro-1,4-methanonaphthalene-2,3-diol
The title compound, C11H12O2, is an intermediate in the synthesis of Varenicline, a nicotinic receptor partial agonist used to treat smoking addiction. In the crystal structure, there is an intramolecular O—H...O hydrogen bond that generates an S(5)
Jian Xu +4 more
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An expanding range of targets for kynurenine metabolites of tryptophan [PDF]
The kynurenine pathway of tryptophan metabolism accounts for most of the tryptophan that is not committed to protein synthesis and includes compounds active in the nervous and immune systems.
Darlington, L. Gail +2 more
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Trimethylsulfonium, a compound present in the midgut gland of the sea hare Aplysia brasiliana, negatively modulates vagal response, indicating a probable ability to inhibit cholinergic responses.
C.M. Kerchove +3 more
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Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core +2 more sources
The antisaccade task as an index of sustained goal activation in working memory: modulation by nicotine [PDF]
The antisaccade task provides a laboratory analogue of situations in which execution of the correct behavioural response requires the suppression of a more prepotent or habitual response.
A Nordberg +64 more
core +1 more source
Wareniklina – częściowy agonista receptorów nikotynowych w terapii zespołu uzależnienia od alkoholu
The pharmacotherapy currently used for alcohol dependence may reduce alcohol consumption and extend abstinence periods. However, it is effective in only about 30% of addicted subjects.
Natalia Obsada +1 more
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Nicotinic acetylcholine receptors containing the α7-like subunit mediate contractions of muscles responsible for space positioning of the snail, Helix pomatia L. tentacle. [PDF]
Three recently discovered tentacle muscles are crucial to perform patterned movements of upper tentacles of the terrestrial snail, Helix pomatia. The muscles receive central and peripheral excitatory cholinergic innervation lacking inhibitory innervation.
Tibor Kiss +3 more
doaj +1 more source
Objective: The aim of the study was to explore the effect of semi-specific antagonists and agonists of the nicotinic acetylcholine receptors on the paired-pulse facilitation and nicotinic tonic and phasic potentiation of the frog retinotectal synaptic ...
Armuntas Baginskas +2 more
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