Results 171 to 180 of about 33,509 (296)

Pancreatic Islet Cell Hormones: Secretion, Function, and Diabetes Therapy

MedComm, Volume 6, Issue 9, September 2025.
The pancreatic islets, composed of α, β, δ, ε, and PP cells, play a central role in maintaining glucose homeostasis. This review examines the mechanisms of islet hormone secretion and their functional crosstalk networks, alongside the pathophysiology of diabetes driven by hormonal dysregulation.
Jinfang Ma, Mao Li, Lingxiao Yang, Qingxing Xie, Rongping Fan, Xi Lu, Xing Huang, Nanwei Tong, Zhenyu Duan   +8 more
wiley   +1 more source

Alpha-7 nicotinic agonists for cognitive deficits in neuropsychiatric disorders: A translational meta-analysis of rodent and human studies. [PDF]

Prog Neuropsychopharmacol Biol Psychiatry, 2017
Lewis AS, van Schalkwyk GI, Bloch MH.
europepmc   +1 more source

Nicotinic agonist locally shot induces non-contractile slow Ca2+ (RAMIC) mobilization at the mouse neuromuscular postsynapse

, 1997
Katsuya Dezaki, Hiroshi Tsuneki, Ikuko Kimura   +2 more
openalex   +1 more source

Invariant Aspartic Acid in Muscle Nicotinic Receptor Contributes Selectively to the Kinetics of Agonist Binding [PDF]

, 2004
Won Yong Lee, Steven M. Sine
openalex   +1 more source

Epigenetic Regulation of Aging and its Rejuvenation

MedComm, Volume 6, Issue 9, September 2025.
This article provides an overview of the epigenetic mechanisms and key targets involved in aging, including DNA methylation, histone modifications, chromatin remodeling, and changes in noncoding RNAs. It also introduces various intervention strategies aimed at reversing epigenetic changes to delay aging and treat diseases.
Yongpan An, Qian Wang, Ke Gao, Chi Zhang, Yanan Ouyang, Ruixiao Li, Zhou Ma, Tong Wu, Lifan Zhou, Zhengwei Xie, Rui Zhang, Guojun Wu   +11 more
wiley   +1 more source

GTS-21, a Nicotinic Agonist, Protects against Neocortical Neuronal Cell Loss Induced by the Nucleus Basalis Magnocellularis Lesion in Rats

, 1997
Masato Nanri, Nobuo Kasahara, Jyunji Yamamoto, Hidekazu Miyake, Hiroshi Watanabe   +4 more
openalex   +1 more source

Modulation of airway inflammation and resistance in mice by a nicotinic receptor agonist [PDF]

, 2005
M-R. Blanchet, Évelyne Israël-Assayag, Yvon Cormier   +2 more
openalex   +1 more source

Impact of Confounding Factors in Human Postmortem Brain Tissues on Gene Expression Profiles: A Comparison of Patients With Schizophrenia, Bipolar Disorder, and Nonpsychiatric Controls

Neuropsychopharmacology Reports, Volume 45, Issue 3, September 2025.
This study examined the impact of confounding factors on gene expression in postmortem brain tissue from individuals with psychiatric disorders. The expression was significantly associated with factors such as pH, RIN, PMI, and storage duration, highlighting the importance of accounting for these variables when interpreting transcriptomic data ...
Masataka Hatano, Atsuko Nagaoka, Kazusa Miyahara, Yuto Hosogai, Risa Shishido, Hideomi Hamasaki, Mizuki Hino, Akiyoshi Kakita, Hiroaki Tomita, Yasuto Kunii, Itaru Miura   +10 more
wiley   +1 more source

The characterization of a novel rigid nicotine analog with α7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion [PDF]

, 2005
Roger L. Papke, Guangrong Zheng, Nicole A. Horenstein, Linda P. Dwoskin, Peter A. Crooks   +4 more
openalex   +1 more source

Use of Antidepressants Decreased After Initiation of ADHD Treatment in Adults—A Finnish Nationwide Register Study Describing Use of ADHD and Non‐ADHD Medication in People With and Without ADHD

Acta Psychiatrica Scandinavica, Volume 152, Issue 3, Page 203-215, September 2025.
ABSTRACT Introduction ADHD is often associated with comorbid psychiatric conditions. Differential diagnosis between other conditions and ADHD is not always clear, and patients are sometimes initially treated for another disorder instead. ADHD diagnosis and appropriate ADHD treatment potentially reduce the need for medication of the other disorder ...
Elisa Westman, Tuire Prami, Alvar Kallio, Ilona Iso‐Mustajärvi, Joel Jukka, Paavo Raittinen, Maarit J. Korhonen, Anita Puustjärvi, Sami Leppämäki   +8 more
wiley   +1 more source